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https://hdl.handle.net/11499/6980
Title: | Evaluation of biofilm production, gelatinase activity, and mannose-resistant hemagglutination in Acinetobacter baumannii strains | Authors: | Cevahir, Nural Demir, Melek Kaleli, İlknur Gurbuz, M. Tikvesli, S. |
Keywords: | Acinetobacter baumannii Biofilms Gelatinases Hemagglutination gelatinase mannose article bacterial colonization bacterial strain bacterial virulence bacterium identification bacterium isolation biofilm blood group AB blood group O clinical evaluation comparative study erythrocyte gelatinization hemagglutination human infection risk major clinical study pathogenesis Acinetobacter Infections Bacterial Proteins Chi-Square Distribution Cross Infection Hemagglutination Tests Hospitals, University Humans Virulence Factors |
Abstract: | Background and Purpose: Acinetobacter baumannii is an important nosocomial pathogen, but its pathogenic characteristics are not well defined. The purpose of this study was to evaluate biofilm production, mannose-resistant hemagglutination, and gelatinase production in A. baumannii strains isolated from various clinical specimens. Methods: Eighty six strains of A. baumannii isolated from 86 hospital inpatients were studied for biofilm formation, gelatinase activity, and mannose-resistant hemagglutination. The isolates were identified using conventional techniques and/or the API 2ONE system. Comparisons of biofilm production, gelatinase activity, and mannose-resistant hemagglutination were made by chi-squared analysis. Results: Twenty two and 61 of the isolates agglutinated human group O and AB erythrocytes in the presence of mannose, respectively. Gelatinase activity was detected in 12 isolates (14%), while 64 isolates formed biofilms. Conclusions: Several parameters may play important roles in causing infection in colonized patients. Identifying the factors that influence virulence may help to separate the colonizing strains into those with high or low potential virulence. © 2008 Journal of Microbiology, Immunology and Infection. | URI: | https://hdl.handle.net/11499/6980 | ISSN: | 1684-1182 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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