Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/7028
Title: Associations of alcohol consumption with blood pressure, lipoproteins, and subclinical inflammation among Turks
Authors: Onat, A.
Hergenc, G.
Dursunoğlu, Dursun
Ordu, S.
Can, G.
Bulur, S.
Yüksel, H.
Keywords: Alcohol consumption
Apolipoprotein B
Blood pressure
C-reactive protein
LDL cholesterol
Metabolic syndrome
alcohol
apolipoprotein B
C reactive protein
low density lipoprotein cholesterol
triacylglycerol
adult
alcohol consumption
article
blood pressure measurement
cardiovascular risk
cholesterol blood level
controlled study
correlation analysis
diastolic blood pressure
drinking behavior
female
human
inflammation
linear regression analysis
lipoprotein blood level
logistic regression analysis
major clinical study
male
metabolic disorder
prospective study
protein blood level
risk assessment
risk reduction
sex difference
systolic blood pressure
triacylglycerol blood level
Turkey (republic)
Adult
Alcohol Drinking
Blood Pressure
C-Reactive Protein
Cross-Sectional Studies
Female
Follow-Up Studies
Humans
Hypertension
Inflammation
Lipoproteins
Male
Middle Aged
Prospective Studies
Risk Factors
Sex Factors
Turkey
Abstract: Gender-related impact of alcohol consumption on blood pressure (BP), serum lipoprotein profile, and C-reactive protein (CRP) concentrations was evaluated prospectively. Alcohol drinking status was assessed as abstainers and categories of light, moderate, and heavy (daily >40 ml ethanol) intake. Mean age of the 3,443 men and women who were followed up for a mean of 7.4 years was 47.6 ± 12 years. In each multivariable linear or logistic regression analysis, alcohol drinking status was adjusted for age, sex, smoking status, and physical activity. Among men, drinking was significantly associated positively with low-density lipo protein (LDL) cholesterol, apolipoprotein (apo) B, systolic and diastolic BP, and with CRP in a log-linear manner exhibiting features of a threshold at heavy drinking. With respect to response of serum triglycerides to light-to-moderate drinking, whereas men exhibited a significant increase, women exhibited a decline (P < .05). Lower BPs (P < .03) and CRP levels (P = .032) were observed in female drinkers than abstainers and, as distinct from men, no increases in LDL cholesterol and apoB were noted. Heavy drinking tended to protect the sexes against the risk of developing low high-density lipoprotein cholesterol levels in prospective multi adjusted analyses. Sex modulates response of cardiometabolic risk variables to moderate alcohol consumption among Turks. Only women respond with lower triglycerides and CRP, whereas men show a log-linear positive association of drinking categories with BP, LDL cholesterol, apoB, and CRP. © 2008 Elsevier Inc. All rights reserved.
URI: https://hdl.handle.net/11499/7028
https://doi.org/10.1016/j.alcohol.2008.06.007
ISSN: 0741-8329
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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