Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/7151
Title: Incidence, prevalence, and mortality estimates for chronic atrial fibrillation in Turkish adults
Authors: Uyarel, H.
Onat, A.
Yüksel, H.
Can, G.
Ordu, S.
Dursunoglu, Dursun.
Keywords: Atrial fibrillation/epidemiology
Cohort studies
Incidence
Prevalence
Sex distribution
Turkey/epidemiology
C reactive protein
adult
aged
aging
article
chronic disease
cross-sectional study
female
heart atrium fibrillation
human
hypertension
incidence
male
metabolism
middle aged
mortality
prevalence
prospective study
risk factor
sex difference
Turkey (republic)
Adult
Aged
Aging
Atrial Fibrillation
C-Reactive Protein
Chronic Disease
Cross-Sectional Studies
Female
Humans
Hypertension
Male
Middle Aged
Prospective Studies
Risk Factors
Sex Factors
Turkey
Abstract: Objectives: We investigated the incidence, prevalence, and mortality of chronic atrial fibrillation (AF) in Turkish adults. Study design: In a prospective and cross-sectional design, we analyzed 3,450 eligible participants (1707 men, 1743 women; mean age 52±13 years) of the Turkish Adult Risk Factor Study, who had been surveyed until 2006/07. Those who were dead and were found to have AF at base-line were excluded in the estimation of AF prevalence and incidence, respectively. Results: Atrial fibrillation was determined in 67 participants. The total follow-up was 34,100 person-years (mean 9.9 years). There were 43 prevalent and 46 incident cases, which corresponded to 1.25% and 1.35 per 1000 person-years, respectively. For age brackets of 32-59, 60-69, and ?70 years, the prevalence rates were 0.46%, 2.09%, and 2.49%, and the incidence rates were 0.31, 1.98, and 3.50 per 1000 person-years, respectively. Both were higher in women of all age groups, with female-to-male ratios for overall prevalence and incidence being 1.69 and 1.19, respectively. Survival after onset of AF was 5 to 9 years and overall mortality was 6.8 per 100 person-years. Hypertension was the most common cause of AF, followed by advanced age. Contrary to expectations, waist circumference of men with AF was smaller by 1.9 cm than that of women. Serum C-reactive protein levels in men with AF (mean 1.21 mg/I) were significantly lower than women with AF (mean 2.62 mg/l) and than males without AF (mean 1.78 mg/l). Conclusion: In Turkish adults, the current incidence and prevalence of chronic AF can be extrapolated to be 35,000 per year (22,000 in women) and 310,000 (200,000 in women), respectively. Considering the low incidence in males, it seems that inflammatory processes may play a minor role in the development of AF in Turkish men.
URI: https://hdl.handle.net/11499/7151
ISSN: 1016-5169
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Show full item record



CORE Recommender

SCOPUSTM   
Citations

35
checked on Oct 13, 2024

WEB OF SCIENCETM
Citations

38
checked on Oct 20, 2024

Page view(s)

66
checked on Aug 24, 2024

Google ScholarTM

Check





Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.