Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/7159
Title: Cerebral lateral ventricular asymmetry on CT: How much asymmetry is representing pathology?
Authors: Kiroglu, Y.
Karabulut, N.
Öncel, Çağatay
Yağcı, Baki
Sabir, Nuran
Özdemir, Bülent
Keywords: Asymmetry
Brain
Computed tomography
Lateral ventricle
adolescent
adult
aged
alcohol consumption
article
ataxia
brain asymmetry
brain region
clinical study
computer assisted tomography
controlled study
correlation analysis
data analysis
density
differential diagnosis
disease severity
female
handedness
headache
hearing impairment
human
hydrocephalus
lateral brain ventricle
major clinical study
male
neurologic disease
nuclear magnetic resonance imaging
prevalence
priority journal
school child
smoking
solid tumor
statistical significance
transient ischemic attack
vertigo
visual disorder
Adolescent
Adult
Aged
Aged, 80 and over
Brain Diseases
Cerebral Ventriculography
Child
Diagnosis, Differential
Female
Headache
Humans
Hydrocephalus
Lateral Ventricles
Male
Middle Aged
Severity of Illness Index
Tomography, X-Ray Computed
Abstract: Purpose: The purpose of this study was to evaluate the association of asymmetric lateral ventricle (ALV) with clinical and structural pathologies and assess its clinical importance. Materials and methods: We analyzed 170 consecutive ALV cases on computed tomography (CT) and 170 control group patients with normal head CT. Patients who had apparent etiologic causes for ALV were excluded. The differential diagnosis of ALV and unilateral hydrocephalus (UH) was made by using three different ventricle-brain ratios (VBRs). The measurements of the ALV were made at the frontal horn level. Patients with asymmetry were divided into three subgroups including mild, moderate and severe groups to eloborate the grade of the ventricular asymmetry. Additional CT findings including septal deviation, diffuse enlargement, atrophy and the densities of constant sites were also recorded systematically for each patient. Clinical and handedness data were collected and analyzed. Results: The prevalence of ALV in the study population was 6.1%. Headache was the most common reason for head CT examination and was significantly more common in the asymmetry group (61.7% in group A, 42.9% in group B, P = 0.001). Transient ischemic attack, focal neurologic findings, vertigo, ataxia, visual and hearing disturbances were similar in both groups (P > 0.5). There was no difference in smoking and alcohol habits in both patient groups. Ten (5.8%) patients in group A and 16 (9.4%) patients in group B had neuropsychiatric disorders, which did not achieve statistical significance. In group A patients, the larger ventricle was more common in the left side than in the right (left = 70.0%, right = 30.0%). Group A consisted of 57.0% mild (grade 1, n = 97), 26.5% moderate (grade II, n = 45) and 16.5% severe (grade III, n = 28) patients. There was no significant correlation between handedness and ALV. The density of different brain sites was found close similar on both sides in ALV and control group (P > 0.5). Choroidal cystic or solid neoplasm or periventricular dysplasia was detected in six ALV patients in group A (3.5%), on their additional MR examinations. Conclusion: The physician should not overlook an ALV finding on unenhanced CT, particularly in cases with severe degree of asymmetry or diffuse ventricular enlargement, and search for possible accompanying disorders. © Springer-Verlag 2008.
URI: https://hdl.handle.net/11499/7159
https://doi.org/10.1007/s00276-008-0314-9
ISSN: 0930-1038
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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