Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/7187
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Çulha, Ateşçi Figen | - |
dc.contributor.author | Özdel, Osman İsmail | - |
dc.contributor.author | Doğangün, Yüksel | - |
dc.contributor.author | Filiz, Karadağ | - |
dc.contributor.author | Suna, Kıraç | - |
dc.contributor.author | Kalkan, Oğuzhanoğlu Nalan | - |
dc.contributor.author | Gülfizar, Varma | - |
dc.date.accessioned | 2019-08-16T12:17:25Z | - |
dc.date.available | 2019-08-16T12:17:25Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0940-1334 | - |
dc.identifier.uri | https://hdl.handle.net/11499/7187 | - |
dc.identifier.uri | https://doi.org/10.1007/s00406-007-0766-7 | - |
dc.description.abstract | Single photon emission computed tomography (SPECT) with 99mTc-HMPAO was used to compare regional cerebral blood flow (rCBF) in patients with bipolar disorder and in healthy controls. The sample of this study consisted of 16 euthymic bipolar patients who met the DSM-IV criteria and 10 healthy control subjects. The mean regional cerebral blood flow values of the bipolar euthymic patients were significantly lower than those of the controls in the bilateral medial-basal temporal, occipital; medial frontal; parietal regions and in the cingulate gyrus; the hypoperfusion in the cingulate had the highest significant P value (.001, Bonferroni correction). No significant differences in rCBF emerged between right and left-brain regions. The most important findings of the current study are the presence of regional cerebral perfusion alterations, particularly in the cingulate gyrus in the euthymic bipolar patients. Our results imply that underlying brain dysfunction may be independent from manic or depressive episodes in bipolar disorder. Because of the small number of subjects, however, this finding should be viewed as preliminary. © 2007 Springer. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | European Archives of Psychiatry and Clinical Neuroscience | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Brain imaging | en_US |
dc.subject | Cerebral perfusion | en_US |
dc.subject | Cingulate gyrus | en_US |
dc.subject | Euthymic bipolar disorder | en_US |
dc.subject | hexamethylpropylene amine oxime technetium tc 99m | en_US |
dc.subject | lithium | en_US |
dc.subject | olanzapine | en_US |
dc.subject | risperidone | en_US |
dc.subject | valproic acid | en_US |
dc.subject | adult | en_US |
dc.subject | article | en_US |
dc.subject | bipolar disorder | en_US |
dc.subject | brain blood flow | en_US |
dc.subject | brain dysfunction | en_US |
dc.subject | brain perfusion | en_US |
dc.subject | brain region | en_US |
dc.subject | cingulate gyrus | en_US |
dc.subject | clinical article | en_US |
dc.subject | controlled study | en_US |
dc.subject | depression | en_US |
dc.subject | diagnostic and statistical manual of mental disorders | en_US |
dc.subject | female | en_US |
dc.subject | frontal lobe | en_US |
dc.subject | human | en_US |
dc.subject | male | en_US |
dc.subject | mania | en_US |
dc.subject | occipital lobe | en_US |
dc.subject | parietal lobe | en_US |
dc.subject | priority journal | en_US |
dc.subject | single photon emission computer tomography | en_US |
dc.subject | temporal lobe | en_US |
dc.subject | Adult | en_US |
dc.subject | Affect | en_US |
dc.subject | Bipolar Disorder | en_US |
dc.subject | Brain | en_US |
dc.subject | Brain Mapping | en_US |
dc.subject | Case-Control Studies | en_US |
dc.subject | Cerebrovascular Circulation | en_US |
dc.subject | Female | en_US |
dc.subject | Humans | en_US |
dc.subject | Male | en_US |
dc.subject | Radiopharmaceuticals | en_US |
dc.subject | Reference Values | en_US |
dc.subject | Technetium Tc 99m Exametazime | en_US |
dc.subject | Tomography, Emission-Computed, Single-Photon | en_US |
dc.title | Changes in regional cerebral blood flow demonstrated by 99mTc-HMPAO SPECT in euthymic bipolar patients | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 258 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 144 | - |
dc.identifier.startpage | 144 | en_US |
dc.identifier.endpage | 151 | en_US |
dc.authorid | 0000-0002-6153-6744 | - |
dc.authorid | 0000-0003-0983-2834 | - |
dc.authorid | 0000-0001-8631-7049 | - |
dc.authorid | 0000-0003-4808-3274 | - |
dc.authorid | 0000-0002-2570-3445 | - |
dc.identifier.doi | 10.1007/s00406-007-0766-7 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 17990047 | en_US |
dc.identifier.scopus | 2-s2.0-43149094446 | en_US |
dc.identifier.wos | WOS:000255646100003 | en_US |
dc.identifier.scopusquality | Q1 | - |
dc.owner | Pamukkale University | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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