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https://hdl.handle.net/11499/7319
Title: | The value of admission glycosylated hemoglobin level in patients with acute myocardial infarction | Authors: | Cakmak, M. Cakmak, N. Cetemen, S. Tanrıverdi, Halil Enc, Y. Teskin, O. Kılıç, İsmail Doğu |
Keywords: | Acute myocardial infarction Diabetes HbA1c Ischemic score Prognosis fibrinolytic agent glucose glycosylated hemoglobin hemoglobin A1c thallium 201 acute heart infarction adult aged angiocardiography article controlled study coronary artery disease exercise test female fibrinolytic therapy follow up glucose blood level heart muscle ischemia heart muscle perfusion hemoglobin blood level hospital admission human major clinical study male mortality obesity prognosis prospective study risk factor sex difference smoking blood heart infarction middle aged Aged Blood Glucose Female Hemoglobin A, Glycosylated Humans Male Middle Aged Myocardial Infarction Prospective Studies Risk Factors |
Publisher: | Pulsus Group Inc. | Abstract: | Background: Glycosylated hemoglobin (HbA1c) level on admission is a prognostic factor for mortality in patients with and without diabetes after myocardial infarction. In the present study, the authors examined the relationship between admission HbA1c level and myocardial perfusion abnormalities in patients with acute myocardial infarction. Methods: One hundred consecutive patients with acute myocardial infarction who were treated with thrombolytic therapy were included in the present prospective study. Blood glucose and HbA1c levels of all patients were measured within 3 h of admission. Patients were divided into three groups according to HbA1c level: 4.5% to 6.4% (n=25), 6.5% to 8.5% (n=28) and higher than 8.5% (n=47). All patients then underwent exercise thallium-201 imaging and coronary angiography to determine ischemic scores and the number of diseased coronary arteries four weeks after admission. Results: Seven patients died within the four-week follow-up period. There was a significant relationship between admission HbA1c level and mortality (P=0.009). Furthermore, there was a significant relationship between HbA1c level and total ischemic scores in patients with acute myocardial infarction (r=0.482; P=0.001). Ischemic scores increased as HbA1c levels increased in patients with acute myocardial infarction. Conclusions: The results demonstrated that admission plasma glucose and HbA1c levels are prognostic factors associated with mortality after acute myocardial infarction. ©2008 Pulsus Group Inc. All rights reserved. | URI: | https://hdl.handle.net/11499/7319 https://doi.org/10.1016/S0828-282X(08)70600-7 |
ISSN: | 0828-282X |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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