Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/7319
Title: The value of admission glycosylated hemoglobin level in patients with acute myocardial infarction
Authors: Cakmak, M.
Cakmak, N.
Cetemen, S.
Tanrıverdi, Halil
Enc, Y.
Teskin, O.
Kılıç, İsmail Doğu
Keywords: Acute myocardial infarction
Diabetes
HbA1c
Ischemic score
Prognosis
fibrinolytic agent
glucose
glycosylated hemoglobin
hemoglobin A1c
thallium 201
acute heart infarction
adult
aged
angiocardiography
article
controlled study
coronary artery disease
exercise test
female
fibrinolytic therapy
follow up
glucose blood level
heart muscle ischemia
heart muscle perfusion
hemoglobin blood level
hospital admission
human
major clinical study
male
mortality
obesity
prognosis
prospective study
risk factor
sex difference
smoking
blood
heart infarction
middle aged
Aged
Blood Glucose
Female
Hemoglobin A, Glycosylated
Humans
Male
Middle Aged
Myocardial Infarction
Prospective Studies
Risk Factors
Publisher: Pulsus Group Inc.
Abstract: Background: Glycosylated hemoglobin (HbA1c) level on admission is a prognostic factor for mortality in patients with and without diabetes after myocardial infarction. In the present study, the authors examined the relationship between admission HbA1c level and myocardial perfusion abnormalities in patients with acute myocardial infarction. Methods: One hundred consecutive patients with acute myocardial infarction who were treated with thrombolytic therapy were included in the present prospective study. Blood glucose and HbA1c levels of all patients were measured within 3 h of admission. Patients were divided into three groups according to HbA1c level: 4.5% to 6.4% (n=25), 6.5% to 8.5% (n=28) and higher than 8.5% (n=47). All patients then underwent exercise thallium-201 imaging and coronary angiography to determine ischemic scores and the number of diseased coronary arteries four weeks after admission. Results: Seven patients died within the four-week follow-up period. There was a significant relationship between admission HbA1c level and mortality (P=0.009). Furthermore, there was a significant relationship between HbA1c level and total ischemic scores in patients with acute myocardial infarction (r=0.482; P=0.001). Ischemic scores increased as HbA1c levels increased in patients with acute myocardial infarction. Conclusions: The results demonstrated that admission plasma glucose and HbA1c levels are prognostic factors associated with mortality after acute myocardial infarction. ©2008 Pulsus Group Inc. All rights reserved.
URI: https://hdl.handle.net/11499/7319
https://doi.org/10.1016/S0828-282X(08)70600-7
ISSN: 0828-282X
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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