Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/7707
Title: | Prednisolone in complex regional pain syndrome | Authors: | Atalay, N.S. Ercidogan, O. Akkaya, Nuray Sahin, F. |
Keywords: | Complex regional pain syndrome Function Prednisolone Quality of life prednisolone adult aged article balneotherapy body temperature disorder clinical article cold intolerance complex regional pain syndrome drug dose reduction exercise female follow up functional assessment grip strength human hyperesthesia male morning stiffness muscle strength pinch strength quality of life retrospective study symptom treatment outcome visual analog scale Adult Anti-Inflammatory Agents Complex Regional Pain Syndromes Disability Evaluation Female Follow-Up Studies Hand Strength Humans Male Middle Aged Pain Measurement Quality of Life Retrospective Studies Treatment Outcome |
Publisher: | Association of Pain Management Anesthesiologists | Abstract: | Background: Although there are several studies of systemic corticosteroid therapies in various doses and various durations in complex regional pain syndrome (CRPS), the outcome measurement parameters are limited to the range of motion measurements, edema, and symptoms of CRPS. Objective: To investigate the effects of prednisolone on clinical symptoms, pain, hand grip strength, range of motion, as well as on functional ability and quality of life in patients who developed CRPS after traumatic upper extremity injury. Study Design: Retrospective evaluation. Methods: Forty-five patients who used prednisolone for CRPS of the upper extremity were retrospectively studied. Prednisolone was started with a dose of 30 mg and tapered by 5 mg every 3 days until discontinuation after 3 weeks. Clinical symptoms (morning stiffness, cold intolerance, shoulder pain, numbness of fingers, hyperesthesia, abnormal sweating, and cyanosis that is exacerbated by exposure to cold temperature), pain (Visual Analogue Scale-Rest [VAS-R] and VASActivity [VAS-A]) were reviewed. The muscle strength with grip strength (GS) (kg), lateral pinch (LP) (pound), tip-to-tip pinch (TP) (pound), and chuck pinch (CP) (pound) measurements; the joint range of motion with using third finger tip-distal crease distance (FT-DC) (cm); functional ability with Quick-Disabilities of the Arm, Shoulder and Hand (Q-DASH) score; and quality of life with Short Form-36 (SF-36) score were evaluated. Results: Mean age was 43.53 ± 11.43 years. After 3 weeks of therapy, patients showed significant improvements in clinical symptoms compared to the basal assessments (P < 0.05). The comparison of pre- and post-treatment results revealed that VAS-R, VAS-A, GS, LP, TP, CP, FT-DC, Q-DASH scores, and all SF-36 subscores were significantly improved (P < 0.05). Limitations: The retrospective design and data collection procedure was limited to the medical records of patients. Conclusion: A short-term oral prednisolone therapy significantly reduced the symptoms and signs of CRPS, and improved the functional abilities and quality of life. | URI: | https://hdl.handle.net/11499/7707 | ISSN: | 1533-3159 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
Show full item record
CORE Recommender
SCOPUSTM
Citations
31
checked on Nov 30, 2024
WEB OF SCIENCETM
Citations
23
checked on Dec 3, 2024
Page view(s)
28
checked on Aug 24, 2024
Google ScholarTM
Check
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.