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https://hdl.handle.net/11499/7871
Title: | Association of serum lipid levels with diabetic retinopathy | Authors: | Çetin, Ebru Nevin Bulgu, Yunus Özdemir, Seyfullah Topsakal, Şenay Akın, Fulya Aybek, Hülya Yıldırım, Cem |
Keywords: | Cholesterol Diabetes mellitus Diabetic retinopathy High density lipoprotein Low density lipoprotein Macular edema Triglyceride |
Abstract: | AIM: To assess the association between serum lipids and diabetic retinopathy (DR). METHODS: Sixty-one diabetic patients without retinopathy (NDR), 55 diabetic patients with non-proliferative retinopathy (NPDR) and 75 diabetic patients with proliferative retinopathy (PDR) according to ETDRS grading scale were enrolled in this study. Total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL) and triglyceride values were compared between the groups. RESULTS: The groups were well-balanced in terms of age and gender (P = 0.071, P = 0.265 respectively). The mean HbA1c values were significantly lower in NDR group than the NPDR and PDR groups (P = 0.004, P = 0.009 respectively). Mean total cholesterol, triglyceride, LDL, HDL and VLDL levels were not significantly different between the groups (P = 0.693, P = 0.774, -P = 0.644, P = 0.910 and P = 0.967 respectively, one way ANOVA). Mean total cholesterol, trigly ceride, LDL, HDL and VLDL levels were not significantly different between the patients with MEand patients without ME (P = 0.622, P = 0.113, P = 0.955, P = 0.735 and P = 0.490 respectively, t-test). The mean blood glucose significantly correlated with total cholesterol (r=0.173, P = 0.017) and LDL (r=0.190, P = 0.008). The mean HbA1c significantly correlated with total cholesterol (r=0.158, P = 0.030) and trigly ceride (r=0.148, P = 0.042). CONCLUSION: Serum lipid levels were not significantly associated with the severity of DR or existence of ME despite the significant correlation between the mean blood glucose, HbA1c and total cholesterol. Copyright International Journal of Ophthalmology Press. | URI: | https://hdl.handle.net/11499/7871 https://doi.org/10.3980/j.issn.2222-3959.2013.03.17 |
ISSN: | 2222-3959 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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