Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/8109
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Menzies, S.W. | - |
dc.contributor.author | Moloney, F.J. | - |
dc.contributor.author | Byth, K. | - |
dc.contributor.author | Avramidis, M. | - |
dc.contributor.author | Argenziano, G. | - |
dc.contributor.author | Zalaudek, I. | - |
dc.contributor.author | Braun, R.P. | - |
dc.date.accessioned | 2019-08-16T12:35:35Z | - |
dc.date.available | 2019-08-16T12:35:35Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 2168-6068 | - |
dc.identifier.uri | https://hdl.handle.net/11499/8109 | - |
dc.identifier.uri | https://doi.org/10.1001/jamadermatol.2013.2466 | - |
dc.description.abstract | Importance: Nodular melanoma (NM) is a rapidly progressing potentially lethal skin tumor for which early diagnosis is critical. Objective: To determine the dermoscopy features of NM. Design: Eighty-three cases of NM, 134 of invasive non- NM, 115 of nodular benign melanocytic tumors, and 135 of nodular nonmelanocytic tumors were scored for dermoscopy features using modified and previously described methods. Lesions were separated into amelanotic/ hypomelanotic or pigmented to assess outcomes. Setting: Predominantly hospital-based clinics from 5 continents. Main Outcome Measures: Sensitivity, specificity, and odds ratios for features/models for the diagnosis of melanoma. Results: Nodular melanoma occurred more frequently as amelanotic/hypomelanotic (37.3%) than did invasive non-NM (7.5%). Pigmented NM had a more frequent (compared with invasive non-NM; in descending order of odds ratio) symmetrical pigmentation pattern (5.8% vs 0.8%), large-diameter vessels, areas of homogeneous blue pigmentation, symmetrical shape, predominant peripheral vessels, blue-white veil, pink color, black color, and milky red/pink areas. Pigmented NM less frequently displayed an atypical broadened network, pigment network or pseudonetwork, multiple blue-gray dots, scarlike depigmentation, irregularly distributed and sized brown dots and globules, tan color, irregularly shaped depigmentation, and irregularly distributed and sized dots and globules of any color. The most important positive correlating features of pigmented NM vs nodular nonmelanoma were peripheral black dots/globules, multiple brown dots, irregular black dots/globules, bluewhite veil, homogeneous blue pigmentation, 5 to 6 colors, and black color. A model to classify a lesion as melanocytic gave a high sensitivity (98.0%) for both nodular pigmented and nonnodular pigmented melanoma but a lower sensitivity for amelanotic/ hypomelanoticNM(84%). A method for diagnosing amelanotic/hypomelanotic malignant lesions (including basal cell carcinoma) gave a 93% sensitivity and 70% specificity for NM. Conclusions and Relevance: When a progressively growing, symmetrically patterned melanocytic nodule is identified, NM needs to be excluded. © 2013 American Medical Association. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | JAMA Dermatology | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | article | en_US |
dc.subject | basal cell carcinoma | en_US |
dc.subject | diagnostic procedure | en_US |
dc.subject | diagnostic test accuracy study | en_US |
dc.subject | epiluminescence microscopy | en_US |
dc.subject | hospital | en_US |
dc.subject | human | en_US |
dc.subject | invasive non nodular melanoma | en_US |
dc.subject | major clinical study | en_US |
dc.subject | medical assessment | en_US |
dc.subject | melanoma | en_US |
dc.subject | nodular benign melanocytic tumor | en_US |
dc.subject | nodular nonmelanocytic tumor | en_US |
dc.subject | outcome assessment | en_US |
dc.subject | priority journal | en_US |
dc.subject | risk | en_US |
dc.subject | scoring system | en_US |
dc.subject | sensitivity and specificity | en_US |
dc.subject | skin pigmentation | en_US |
dc.subject | skin tumor | en_US |
dc.subject | Dermoscopy | en_US |
dc.subject | Disease Progression | en_US |
dc.subject | Humans | en_US |
dc.subject | Melanoma | en_US |
dc.subject | Pigmentation | en_US |
dc.subject | Sensitivity and Specificity | en_US |
dc.subject | Skin Neoplasms | en_US |
dc.title | Dermoscopic evaluation of nodular melanoma | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 149 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 699 | |
dc.identifier.startpage | 699 | en_US |
dc.identifier.endpage | 709 | en_US |
dc.identifier.doi | 10.1001/jamadermatol.2013.2466 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 23553375 | en_US |
dc.identifier.scopus | 2-s2.0-84879330371 | en_US |
dc.identifier.wos | WOS:000320857700008 | en_US |
dc.identifier.scopusquality | Q1 | - |
dc.owner | Pamukkale University | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.languageiso639-1 | en | - |
item.fulltext | With Fulltext | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
Files in This Item:
File | Size | Format | |
---|---|---|---|
15165430.pdf | 548.1 kB | Adobe PDF | View/Open |
CORE Recommender
SCOPUSTM
Citations
86
checked on Oct 13, 2024
WEB OF SCIENCETM
Citations
72
checked on Oct 22, 2024
Page view(s)
78
checked on Aug 24, 2024
Download(s)
12
checked on Aug 24, 2024
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.