Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8166
Title: Effects of high thoracic epidural anesthesia on mixed venous oxygen saturation in coronary artery bypass grafting surgery
Authors: Gürses, Ercan Lütfi
Berk, Derviş
Sungurtekin, Hülya
Mete, Aslı
Serin, Simay
Keywords: Coronary arteries bypass grafting surgery
Mixed venous oxygen saturation
Thoracic epidural anesthesia
analgesic agent
adult
aged
article
bispectral index
body temperature
central venous pressure
coronary artery bypass graft
extubation
female
heart index
heart output
heart rate
hematocrit
hemodynamic parameters
human
lung artery pressure
lung compliance
lung vascular resistance
major clinical study
male
mean arterial pressure
oxygen saturation
prospective study
pulmonary artery occlusion pressure
systemic vascular resistance
thorax epidural anesthesia
transfusion
vasodilatation
visual analog scale
Adult
Aged
Anesthesia, Epidural
Coronary Artery Bypass
Demography
Female
Hemodynamics
Humans
Intraoperative Care
Male
Middle Aged
Oxygen
Postoperative Complications
Respiration
Veins
Abstract: Background: To investigate possible effects of high thoracic epidural anesthesia (HTEA) on mixed venous oxygen saturation (SvO2) in coronary artery bypass grafting surgery (CABGS). Material/Methods: Sixty-four patients scheduled for CABGS were randomly assigned to either test (HTEA) or control group. Standard balanced general anesthesia was applied in both groups. Mean arterial blood pressure (MAP), heart rate (HR), oxygen saturation (SpO2), central venous pressure (CVP), cardiac output (CO), cardiac index (CI), systemic vascular resistance (SVR), pulmonary vascular resistance (PVR), mean pulmonary arterial pressure (PAP), pulmonary capillary wedge pressure (PCWP), pulmonary compliance (C), bispectral index (BIS), body temperature, SvO2, hematocrit values were recorded before induction. Postoperative hemodynamic changes, inotropic agent, need for vasodilatation, transfusion and additional analgesics, recovery score, extubation time, visual analogue scale (VAS) values, duration of stay in intensive care unit (ICU) and hospital were recorded. Results: Study groups were similar in SpO2, CVP, PCWP, PAP, C, body temperature, BIS values, development of intraoperative bradycardia. In HTEA group, intraoperative MAP, SVR, PVR, need for transfusion were lower, whereas CO, CI, SvO2, hematocrit values were higher (p<0.05). Postoperative MAP, HR, hypertension development, need for vasodilatator, transfusion, analgesics, extubation time, recovery data, duration of stay in ICU, hospital were lower in HTEA group (p<0.05). VAS score decreased in 30 minutes and 12 hours following extubation in HTEA and control group, respectively. Conclusions: HTEA may improve balance between oxygen presentation and usage by suppressing neuroendocrin stress response; provide efficient postoperative analgesia, more stabile hemodynamic, respiratory conditions, lower duration of stay in ICU, hospital. © Med Sci Monit.
URI: https://hdl.handle.net/11499/8166
https://doi.org/10.12659/MSM.883861
ISSN: 1234-1010
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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