Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8248
Title: Correlation between blink reflex abnormalities and magnetic resonance imaging findings in patients with multiple sclerosis
Authors: Degirmenci, Eylem
Erdogan, C.
Bir, L.S.
Keywords: Blink reflex test
Brainstem
Magnetic resonance imaging
Multiple sclerosis
adult
article
brain stem
clinical article
controlled study
electrophysiology
electrostimulation
Expanded Disability Status Scale
eyelid reflex
female
human
latent period
male
medulla oblongata
multiple sclerosis
nerve excitability
nuclear magnetic resonance imaging
reflex disorder
Adult
Blinking
Brain Stem
Disability Evaluation
Electromyography
Female
Functional Laterality
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Multiple Sclerosis
Ocular Motility Disorders
Reaction Time
Statistics as Topic
Statistics, Nonparametric
Publisher: Springer-Verlag Italia s.r.l.
Abstract: This study investigates the correlation between brain magnetic resonance imaging findings and blink reflex abnormalities in patients with relapsing remitting multiple sclerosis. Twenty-six patients and 17 healthy subjects were included in this study. Blink reflex test (BRT) results were obtained using right and left stimulations; thus, 52 BRT results were recorded for the patient group, and 34 BRT results were recorded for the control group. The magnetic resonance imaging (MRI) findings were classified based on the existence of brainstem lesions (hyperintense lesion on T2 weighted (W) and fast fluid-attenuated inversion recovery MRI or contrast-enhancing lesion on T1W MRI). Correlation analysis was performed for the BRT and MRI findings. The percentage of individuals with abnormal BRT results (including R1 latency, ipsilateral R2 latency, and contralateral R2 latency) was significantly higher in the patient group as compared to the control group (p values: 0.015, 0.001, and 0.002, respectively). Correlation analysis revealed significant correlations between contralateral R2 latency abnormalities and brainstem lesions (p value: 0.011). Our results showed significant correlation correlations between contralateral R2 latency abnormalities and brainstem lesions and these results may be explained the effects of multiple demyelinating lesions of the brain stem of patients with relapsing remitting multiple sclerosis. © 2013 Belgian Neurological Society.
URI: https://hdl.handle.net/11499/8248
https://doi.org/10.1007/s13760-012-0175-1
ISSN: 0300-9009
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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