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https://hdl.handle.net/11499/8248
Title: | Correlation between blink reflex abnormalities and magnetic resonance imaging findings in patients with multiple sclerosis | Authors: | Degirmenci, Eylem Erdogan, C. Bir, L.S. |
Keywords: | Blink reflex test Brainstem Magnetic resonance imaging Multiple sclerosis adult article brain stem clinical article controlled study electrophysiology electrostimulation Expanded Disability Status Scale eyelid reflex female human latent period male medulla oblongata multiple sclerosis nerve excitability nuclear magnetic resonance imaging reflex disorder Adult Blinking Brain Stem Disability Evaluation Electromyography Female Functional Laterality Humans Magnetic Resonance Imaging Male Middle Aged Multiple Sclerosis Ocular Motility Disorders Reaction Time Statistics as Topic Statistics, Nonparametric |
Publisher: | Springer-Verlag Italia s.r.l. | Abstract: | This study investigates the correlation between brain magnetic resonance imaging findings and blink reflex abnormalities in patients with relapsing remitting multiple sclerosis. Twenty-six patients and 17 healthy subjects were included in this study. Blink reflex test (BRT) results were obtained using right and left stimulations; thus, 52 BRT results were recorded for the patient group, and 34 BRT results were recorded for the control group. The magnetic resonance imaging (MRI) findings were classified based on the existence of brainstem lesions (hyperintense lesion on T2 weighted (W) and fast fluid-attenuated inversion recovery MRI or contrast-enhancing lesion on T1W MRI). Correlation analysis was performed for the BRT and MRI findings. The percentage of individuals with abnormal BRT results (including R1 latency, ipsilateral R2 latency, and contralateral R2 latency) was significantly higher in the patient group as compared to the control group (p values: 0.015, 0.001, and 0.002, respectively). Correlation analysis revealed significant correlations between contralateral R2 latency abnormalities and brainstem lesions (p value: 0.011). Our results showed significant correlation correlations between contralateral R2 latency abnormalities and brainstem lesions and these results may be explained the effects of multiple demyelinating lesions of the brain stem of patients with relapsing remitting multiple sclerosis. © 2013 Belgian Neurological Society. | URI: | https://hdl.handle.net/11499/8248 https://doi.org/10.1007/s13760-012-0175-1 |
ISSN: | 0300-9009 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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