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https://hdl.handle.net/11499/8452
Title: | Comparing the efficacy of mature mud pack and hot pack treatments for knee osteoarthritis | Authors: | Sarsan, Aayşe Akkaya, Nuray. Özgen, M. Yıldız, Necmettin Atalay, Nilgün Şimşir Ardıç, Füsun |
Keywords: | Knee osteoarthritis mud pack therapy quality of life interleukin 6 somatomedin C tumor necrosis factor alpha adult article clinical article clinical feature compression therapy controlled study disability follow up hot pack human knee osteoarthritis mud pack pain assessment physical activity priority journal protein blood level randomized controlled trial rigidity Short Form 36 single blind procedure social status treatment outcome visual analog scale Humans Hyperthermia, Induced Insulin-Like Growth Factor I Interleukin-6 Middle Aged Mud Therapy Osteoarthritis, Knee Pain Management Pain Measurement Prospective Studies Quality of Life Single-Blind Method Treatment Outcome Tumor Necrosis Factor-alpha |
Abstract: | Objective: The objective of this study is to compare the efficacy of mature mud pack and hot pack therapies on patients with knee osteoarthritis. Design: This study was designed as a prospective, randomized-controlled, and single-blinded clinical trial. Twenty-seven patients with clinical and radiologic evidence of knee osteoarthritis were randomly assigned into two groups and were treated with mature mud packs (n 15) or hot packs (n=12). Patients were evaluated for pain [based on the visual analog scale (VAS)], function (WOMAC, 6 min walking distance), quality of life [Short Form-36 (SF-36)], and serum levels of tumor necrosis factor-alpha (TNF-?), interleukin-6 (IL-6), and insulin-like growth factor-1 (IGF-1) at baseline, post-treatment, and 3 and 6~months after treatment. Results: The mud pack group shows a significant improvement in VAS, pain, stifness, and physical function domains of WOMAC. The difference between groups of pain and physical activity domains is significant at post-treatment in favor of mud pack. For a 6 min walking distance, mud pack shows significant improvement, and the difference is significant between groups in favor of mud pack at post-treatment and 3 and 6 months after treatment. Mud pack shows significant improvement in the pain subscale of SF-36 at the third month continuing until the sixth month after the treatment. Significant improvements are found for the social function, vitality/energy, physical role disability, and general health subscales of SF-36 in favor of the mud pack compared with the hot pack group at post-treatment. A significant increase is detected for IGF-1 in the mud pack group 3 months after treatment compared with the baseline, and the difference is significant between groups 3 months after the treatment. Conclusion: Mud pack is a favorable option compared with hotpack for pain relief and for the improvement of functional conditions in treating patients with knee osteoarthritis. © 2012 - IOS Press and the authors. All rights reserved. | URI: | https://hdl.handle.net/11499/8452 https://doi.org/10.3233/BMR-2012-0327 |
ISSN: | 1053-8127 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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