Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8452
Title: Comparing the efficacy of mature mud pack and hot pack treatments for knee osteoarthritis
Authors: Sarsan, Aayşe
Akkaya, Nuray.
Özgen, M.
Yıldız, Necmettin
Atalay, Nilgün Şimşir
Ardıç, Füsun
Keywords: Knee osteoarthritis
mud pack therapy
quality of life
interleukin 6
somatomedin C
tumor necrosis factor alpha
adult
article
clinical article
clinical feature
compression therapy
controlled study
disability
follow up
hot pack
human
knee osteoarthritis
mud pack
pain assessment
physical activity
priority journal
protein blood level
randomized controlled trial
rigidity
Short Form 36
single blind procedure
social status
treatment outcome
visual analog scale
Humans
Hyperthermia, Induced
Insulin-Like Growth Factor I
Interleukin-6
Middle Aged
Mud Therapy
Osteoarthritis, Knee
Pain Management
Pain Measurement
Prospective Studies
Quality of Life
Single-Blind Method
Treatment Outcome
Tumor Necrosis Factor-alpha
Abstract: Objective: The objective of this study is to compare the efficacy of mature mud pack and hot pack therapies on patients with knee osteoarthritis. Design: This study was designed as a prospective, randomized-controlled, and single-blinded clinical trial. Twenty-seven patients with clinical and radiologic evidence of knee osteoarthritis were randomly assigned into two groups and were treated with mature mud packs (n 15) or hot packs (n=12). Patients were evaluated for pain [based on the visual analog scale (VAS)], function (WOMAC, 6 min walking distance), quality of life [Short Form-36 (SF-36)], and serum levels of tumor necrosis factor-alpha (TNF-?), interleukin-6 (IL-6), and insulin-like growth factor-1 (IGF-1) at baseline, post-treatment, and 3 and 6~months after treatment. Results: The mud pack group shows a significant improvement in VAS, pain, stifness, and physical function domains of WOMAC. The difference between groups of pain and physical activity domains is significant at post-treatment in favor of mud pack. For a 6 min walking distance, mud pack shows significant improvement, and the difference is significant between groups in favor of mud pack at post-treatment and 3 and 6 months after treatment. Mud pack shows significant improvement in the pain subscale of SF-36 at the third month continuing until the sixth month after the treatment. Significant improvements are found for the social function, vitality/energy, physical role disability, and general health subscales of SF-36 in favor of the mud pack compared with the hot pack group at post-treatment. A significant increase is detected for IGF-1 in the mud pack group 3 months after treatment compared with the baseline, and the difference is significant between groups 3 months after the treatment. Conclusion: Mud pack is a favorable option compared with hotpack for pain relief and for the improvement of functional conditions in treating patients with knee osteoarthritis. © 2012 - IOS Press and the authors. All rights reserved.
URI: https://hdl.handle.net/11499/8452
https://doi.org/10.3233/BMR-2012-0327
ISSN: 1053-8127
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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