Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8499
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dc.contributor.authorErken, H.A.-
dc.contributor.authorErken, G.-
dc.contributor.authorGen, O.-
dc.contributor.authorKortunay, Selim-
dc.contributor.authorAhiner, M.-
dc.contributor.authorTurgut, Günfer-
dc.contributor.authorTurgut, Sebahat-
dc.date.accessioned2019-08-16T12:41:21Z
dc.date.available2019-08-16T12:41:21Z
dc.date.issued2012-
dc.identifier.isbn01969781 (ISSN)-
dc.identifier.urihttps://hdl.handle.net/11499/8499-
dc.identifier.urihttps://doi.org/10.1016/j.peptides.2012.06.012-
dc.description.abstractOrexins have been implicated in the regulation of sleep-wake cycle, energy homeostasis, drinking behavior, analgesia, attention, learning and memory but their effects on epileptic activity are controversial. We investigated whether intracortical injections of orexin A (100 pmol) and B (100 pmol) cause epileptic activity in rats. We observed epileptic seizure findings on these two groups rats. Orexin A and B also significantly increased total EEG power spectrum. Our findings indicate that orexins cause epileptic activity. © 2012 Elsevier Inc.en_US
dc.language.isoenen_US
dc.relation.ispartofPeptidesen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEEGen_US
dc.subjectEpilepsyen_US
dc.subjectHypocretinen_US
dc.subjectOrexinen_US
dc.subjectPower spectrumen_US
dc.subjectSeizureen_US
dc.subjectorexinen_US
dc.subjectsodium chlorideen_US
dc.subjectanesthesiaen_US
dc.subjectanimal experimenten_US
dc.subjectanimal modelen_US
dc.subjectarticleen_US
dc.subjectbrain cortexen_US
dc.subjectcontrolled studyen_US
dc.subjectelectroencephalogramen_US
dc.subjectepileptic stateen_US
dc.subjectmaleen_US
dc.subjectnonhumanen_US
dc.subjectpriority journalen_US
dc.subjectraten_US
dc.subjectseizureen_US
dc.subjecttonic clonic seizureen_US
dc.subjectAnimalsen_US
dc.subjectDisease Models, Animalen_US
dc.subjectElectroencephalographyen_US
dc.subjectInjections, Intraventricularen_US
dc.subjectIntracellular Signaling Peptides and Proteinsen_US
dc.subjectMaleen_US
dc.subjectNeuropeptidesen_US
dc.subjectNeurotransmitter Agentsen_US
dc.subjectRatsen_US
dc.subjectRats, Wistaren_US
dc.subjectRattusen_US
dc.titleOrexins cause epileptic activityen_US
dc.typeArticleen_US
dc.identifier.volume37en_US
dc.identifier.issue1en_US
dc.identifier.startpage161
dc.identifier.startpage161en_US
dc.identifier.endpage164en_US
dc.authorid0000-0002-7884-5623-
dc.identifier.doi10.1016/j.peptides.2012.06.012-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid22771311en_US
dc.identifier.scopus2-s2.0-84865244135en_US
dc.identifier.wosWOS:000308899100023en_US
dc.ownerPamukkale University-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.openairetypeArticle-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.03. Basic Medical Sciences-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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