Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8540
Full metadata record
DC FieldValueLanguage
dc.contributor.authorYaren, Arzu-
dc.contributor.authorTurgut, Sebahat-
dc.contributor.authorAyada, Ceylan-
dc.contributor.authorAkcılar, Raziye-
dc.contributor.authorDeğirmencioğlu, Serkan-
dc.contributor.authorGököz Doğu, Gamze-
dc.date.accessioned2019-08-16T12:42:08Z
dc.date.available2019-08-16T12:42:08Z
dc.date.issued2012-
dc.identifier.issn0378-1119-
dc.identifier.urihttps://hdl.handle.net/11499/8540-
dc.identifier.urihttps://doi.org/10.1016/j.gene.2012.04.078-
dc.description.abstractWe aimed to assess the association between IGF-I gene (CA repeats) polymorphism in breast cancer patients and their clinicopathological features, as well as disease recurrence and survival. Seventy-six non-metastatic breast cancer patients were enrolled in the present study. The IGF-I (CA) repeats were studied with polymerase chain reaction by using proper primers belonging to these gene areas from DNA samples. Results show that the non 19- non 19 homozygote were more common in patients without lymph node involvement (p = 0.04), with low histological grade (p = 0.04), with positive hormone receptor status (p = 0.01), and in patients without recurrence (p = 0.06). These results suggest that the non 19-non 19 carriers have some favorable prognostic factors, and IGF-I gene polymorphism (CA repeats) may affect disease recurrence and overall survival. © 2012 Elsevier B.V.en_US
dc.language.isoenen_US
dc.relation.ispartofGeneen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreast canceren_US
dc.subjectGene polymorphismen_US
dc.subjectInsulin-like growth factoren_US
dc.subjectPrognosisen_US
dc.subjectantineoplastic agenten_US
dc.subjectDNAen_US
dc.subjectinsulin like growth factor 1 proteinen_US
dc.subjectsomatomedinen_US
dc.subjectunclassified drugen_US
dc.subjectadjuvant therapyen_US
dc.subjectadulten_US
dc.subjectarticleen_US
dc.subjectaxillary lymph nodeen_US
dc.subjectbreast canceren_US
dc.subjectcancer adjuvant therapyen_US
dc.subjectcancer radiotherapyen_US
dc.subjectcancer recurrenceen_US
dc.subjectcancer survivalen_US
dc.subjectclinical featureen_US
dc.subjectDNA polymorphismen_US
dc.subjectfemaleen_US
dc.subjectgenetic analysisen_US
dc.subjecthumanen_US
dc.subjectlymph node dissectionen_US
dc.subjectmajor clinical studyen_US
dc.subjectmastectomyen_US
dc.subjectneoplasmen_US
dc.subjectoverall survivalen_US
dc.subjectpartial mastectomyen_US
dc.subjectpriority journalen_US
dc.subjectAdulten_US
dc.subjectAgeden_US
dc.subjectAged, 80 and overen_US
dc.subjectBreast Neoplasmsen_US
dc.subjectDisease-Free Survivalen_US
dc.subjectFemaleen_US
dc.subjectHumansen_US
dc.subjectInsulin-Like Growth Factor Ien_US
dc.subjectMiddle Ageden_US
dc.subjectNeoplasm Recurrence, Localen_US
dc.subjectPolymorphism, Geneticen_US
dc.titleInsulin-like growth factor I (Igf-1) gene polymorphism in patients with non-metastatic breast canceren_US
dc.typeArticleen_US
dc.identifier.volume503en_US
dc.identifier.issue2en_US
dc.identifier.startpage244
dc.identifier.startpage244en_US
dc.identifier.endpage247en_US
dc.authorid0000-0002-7884-5623-
dc.authorid0000-0002-6272-4173-
dc.authorid0000-0003-4720-1945-
dc.authorid0000-0002-1213-2778-
dc.authorid0000-0001-8142-0362-
dc.identifier.doi10.1016/j.gene.2012.04.078-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid22564703en_US
dc.identifier.scopus2-s2.0-84861823330en_US
dc.identifier.wosWOS:000309249400009en_US
dc.identifier.scopusqualityQ1-
dc.ownerPamukkale University-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.grantfulltextnone-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Show simple item record



CORE Recommender

SCOPUSTM   
Citations

7
checked on Oct 13, 2024

WEB OF SCIENCETM
Citations

7
checked on Oct 20, 2024

Page view(s)

44
checked on Aug 24, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.