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https://hdl.handle.net/11499/8540
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yaren, Arzu | - |
dc.contributor.author | Turgut, Sebahat | - |
dc.contributor.author | Ayada, Ceylan | - |
dc.contributor.author | Akcılar, Raziye | - |
dc.contributor.author | Değirmencioğlu, Serkan | - |
dc.contributor.author | Gököz Doğu, Gamze | - |
dc.date.accessioned | 2019-08-16T12:42:08Z | |
dc.date.available | 2019-08-16T12:42:08Z | |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0378-1119 | - |
dc.identifier.uri | https://hdl.handle.net/11499/8540 | - |
dc.identifier.uri | https://doi.org/10.1016/j.gene.2012.04.078 | - |
dc.description.abstract | We aimed to assess the association between IGF-I gene (CA repeats) polymorphism in breast cancer patients and their clinicopathological features, as well as disease recurrence and survival. Seventy-six non-metastatic breast cancer patients were enrolled in the present study. The IGF-I (CA) repeats were studied with polymerase chain reaction by using proper primers belonging to these gene areas from DNA samples. Results show that the non 19- non 19 homozygote were more common in patients without lymph node involvement (p = 0.04), with low histological grade (p = 0.04), with positive hormone receptor status (p = 0.01), and in patients without recurrence (p = 0.06). These results suggest that the non 19-non 19 carriers have some favorable prognostic factors, and IGF-I gene polymorphism (CA repeats) may affect disease recurrence and overall survival. © 2012 Elsevier B.V. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Gene | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Breast cancer | en_US |
dc.subject | Gene polymorphism | en_US |
dc.subject | Insulin-like growth factor | en_US |
dc.subject | Prognosis | en_US |
dc.subject | antineoplastic agent | en_US |
dc.subject | DNA | en_US |
dc.subject | insulin like growth factor 1 protein | en_US |
dc.subject | somatomedin | en_US |
dc.subject | unclassified drug | en_US |
dc.subject | adjuvant therapy | en_US |
dc.subject | adult | en_US |
dc.subject | article | en_US |
dc.subject | axillary lymph node | en_US |
dc.subject | breast cancer | en_US |
dc.subject | cancer adjuvant therapy | en_US |
dc.subject | cancer radiotherapy | en_US |
dc.subject | cancer recurrence | en_US |
dc.subject | cancer survival | en_US |
dc.subject | clinical feature | en_US |
dc.subject | DNA polymorphism | en_US |
dc.subject | female | en_US |
dc.subject | genetic analysis | en_US |
dc.subject | human | en_US |
dc.subject | lymph node dissection | en_US |
dc.subject | major clinical study | en_US |
dc.subject | mastectomy | en_US |
dc.subject | neoplasm | en_US |
dc.subject | overall survival | en_US |
dc.subject | partial mastectomy | en_US |
dc.subject | priority journal | en_US |
dc.subject | Adult | en_US |
dc.subject | Aged | en_US |
dc.subject | Aged, 80 and over | en_US |
dc.subject | Breast Neoplasms | en_US |
dc.subject | Disease-Free Survival | en_US |
dc.subject | Female | en_US |
dc.subject | Humans | en_US |
dc.subject | Insulin-Like Growth Factor I | en_US |
dc.subject | Middle Aged | en_US |
dc.subject | Neoplasm Recurrence, Local | en_US |
dc.subject | Polymorphism, Genetic | en_US |
dc.title | Insulin-like growth factor I (Igf-1) gene polymorphism in patients with non-metastatic breast cancer | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 503 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 244 | |
dc.identifier.startpage | 244 | en_US |
dc.identifier.endpage | 247 | en_US |
dc.authorid | 0000-0002-7884-5623 | - |
dc.authorid | 0000-0002-6272-4173 | - |
dc.authorid | 0000-0003-4720-1945 | - |
dc.authorid | 0000-0002-1213-2778 | - |
dc.authorid | 0000-0001-8142-0362 | - |
dc.identifier.doi | 10.1016/j.gene.2012.04.078 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 22564703 | en_US |
dc.identifier.scopus | 2-s2.0-84861823330 | en_US |
dc.identifier.wos | WOS:000309249400009 | en_US |
dc.identifier.scopusquality | Q1 | - |
dc.owner | Pamukkale University | - |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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