Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8553
Title: Cantharidin-podophylotoxin-salicylic acid versus cryotherapy in the treatment of plantar warts: A randomized prospective study
Authors: Kaçar, Nida
Taşlı, Mehmet Levent
Korkmaz, Sinem
Ergin, Şeniz
Erdogan, Berna Şanlı
Keywords: antibiotic agent
antiinfective agent
cantharidin
cicatrizing agent
dermatological agent
podophyllotoxin
salicylic acid
unclassified drug
adult
aerosol
antibiotic therapy
application site pain
article
clinical article
clinical assessment
controlled study
cryotherapy
drug efficacy
female
follow up
human
male
priority journal
prospective study
randomized controlled trial
treatment duration
treatment indication
treatment outcome
treatment response
verruca plantaris
Adolescent
Adult
Cantharidin
Combined Modality Therapy
Cryotherapy
Female
Foot
Humans
Male
Podophyllotoxin
Prospective Studies
Salicylic Acid
Warts
Young Adult
Abstract: Background Plantar warts are refractory to any form of treatment. High cure rates have been reported with a topical proprietary formulation consisting of 1% cantharidin, 5% podophyllotoxin and 30% salicylic acid (CPS). However, no data exists comparing the efficacy of this formulation with another treatment. Cryotherapy is a method that is also widely used in the treatment of plantar warts. Likewise, there is no evidence that it is more effective than any topical treatment. Objective We aim to compare the efficacy of topical CPS and cryotherapy in the treatment of plantar warts. Methods Patients with plantar warts were consecutively treated with either cryotherapy or topical CPS. Both treatments were performed every 2 weeks for up to five sessions. In patients without complete clearance, the therapy was switched to the other treatment option. Results Twenty-six patients with a total of 134 warts were included. Fourteen patients were completely cleared of their warts with topical CPS, whereas only in five of 12 patients (41.7%) warts were completely cleared with cryotherapy (P = 0.001). In seven patients without complete clearance, the therapy was switched to CPS. Four of these patients missed the follow-up. While the two of the remaining three patients were cleared of their warts, one patient's warts still failed to clear. Conclusion Topical CPS is more effective than cryotherapy in the treatment of plantar warts. © 2011 European Academy of Dermatology and Venereology.
URI: https://hdl.handle.net/11499/8553
https://doi.org/10.1111/j.1468-3083.2011.04186.x
ISSN: 0926-9959
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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