Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8603
Title: Paroxetine induced platelet dysfunction: A case report
Authors: Sözeri-Varma, Gülfizar
Çulha-Ateşçi, Figen
Keskin, Ali
Şimşek, Deniz
Keywords: Hemorrhage
Paroxetine
Platelet dysfunction
paroxetine
article
case report
conjunctival hemorrhage
epistaxis
human
mental disease
thrombocyte dysfunction
vagina bleeding
Abstract: Paroxetine is a selective serotonin reuptake inhibitor (SSRI) a widely prescribed for the treatment of many psychiatric disorders. Paroxetine inhibits uptake of blood serotonin by platelets and leads to depletion of intraplatelet serotonin. Since serotonin is involved in platelet aggregation, this depletion of serotonin can potentially lead to a higher risk of bleeding. Moreover, hyperserotonemia can cause skin and mucous membrane lesions, such as dilated capillaries or telangiectasia that may cause bleeding without any hemostatic defect. In the present, we report a patient with epistaxis, hyposphagma (hemorrhage into the conjunctiva), and massive vaginal hemorrhage intakes paroxetine.
URI: https://hdl.handle.net/11499/8603
ISSN: 1300-8773
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu

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