Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8630
Title: Neurological soft signs in schizophrenia and obsessive compulsive disorder spectrum
Authors: Tümkaya, Selim
Karadağ, Filiz
Oğuzhanoğlu, Nalan Kalkan
Keywords: Neurological soft signs
Obsessive compulsive disorder
Obsessive compulsive disorder with poor insight
Schizo-obsessive disorder
Schizophrenia
neuroleptic agent
risperidone
adult
article
binocular convergence
disease duration
female
Hamilton scale
human
male
motor coordination
neurologic disease
neurological soft sign
obsessive compulsive disorder
pattern recognition
priority journal
reflex
schizophrenia
synkinesis
tremor
Adult
Diagnostic and Statistical Manual of Mental Disorders
Female
Humans
Male
Middle Aged
Neurologic Examination
Obsessive-Compulsive Disorder
Abstract: Obsessive compulsive symptoms are more frequent in patients with schizophrenia compared to normal population. Patients with obsessive compulsive disorder may also exhibit psychosis-like symptoms. Based on these findings, it has been suggested that there is a spectrum of disorders between OCD and schizophrenia. We compared two OCD groups (with good and poor insight) and two schizophrenia groups (with and without OCD) in this recommended spectrum especially in terms of neurological soft signs (NSSs) associated with sensory integration. The schizophrenia with OCD (schizo-obsessive) group exhibited worse performance than the schizophrenia group (p= 0.002) in only graphesthesia tasks. Moreover, schizo-obsessive patients exhibited worse performance compared to OCD patients in terms of graphesthesia (p= 0.001) and audiovisual integration (p= 0.001). Interestingly, OCD patients with poor insight tended to exhibit graphesthesia deficit in a similar manner to schizo-obsessive patients rather than OCD patients. According to our results, graphesthesia disorder is strongly associated both with OCD and schizophrenia. This suggests that neurodevelopmental disorders that lead to graphesthesia disorder overlap in comorbid OCD and schizophrenia patients. © 2010 Elsevier Masson SAS.
URI: https://hdl.handle.net/11499/8630
https://doi.org/10.1016/j.eurpsy.2010.03.005
ISSN: 0924-9338
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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