Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8693
Title: Is short course of antimicrobial therapy for asymptomatic bacteriuria before urologic surgical procedures sufficient?
Authors: Kutlu, Selda Sayın
Aybek, Zafer
Tekin, K.
Okke, D.
Akalin, S.
Altintas, S.
Demir, Melek
Keywords: Antimicrobial
Bacteriuria
Urologic surgical procedures
antibiotic agent
imipenem
Acinetobacter baumannii
adult
antibiotic sensitivity
antibiotic therapy
article
bacteriuria
Candida tropicalis
clinical article
drug cost
drug efficacy
Escherichia coli
extracorporeal lithotripsy
female
hospitalization
human
Klebsiella pneumoniae
length of stay
male
medical record review
nephrostomy
Pseudomonas aeruginosa
retrospective study
sepsis
transurethral resection
treatment duration
urinary catheter
urologic surgery
Adult
Aged
Aged, 80 and over
Anti-Infective Agents
Female
Humans
Male
Microbial Sensitivity Tests
Middle Aged
Preoperative Care
Sepsis
Time Factors
Treatment Outcome
Urologic Surgical Procedures
Abstract: Introduction: Duration of treatment of asymptomatic bacteriuria for patients undergoing urologic surgical procedures is undetermined. We compared the efficacy of long- versus short-course antimicrobial treatment in patients with asymptomatic bacteriuria undergoing urologic surgical procedures. Methodology: Patients were divided into two groups according to duration of antimicrobial treatment. Group A patients received a single dose of an appropriate antibiotic, determined by antimicrobial sensitivity testing, 30 to 60 minutes before the surgical procedure. If a urinary catheter was placed postoperatively, a second dose was given following the recommended dose interval. Group B patients received antimicrobial treatment prior to surgery at least until patient urine became sterile. All patients were monitored for signs and symptoms of septicemia following surgical procedures. Results: None of the patients enrolled in the study developed infectious complications such as sepsis or upper urinary tract infection. In group A, 31 patients were treated with antimicrobials before 39 urological procedures. In group B, the mean treatment time for 28 patients before 30 urological procedures was 8.03 ± 3.86 days. There were also significant differences in length of stay and the cost of antimicrobial therapy between the groups (P < 0.0001). Isolation of an increased number of resistant microorganisms was associated with long course therapy in group B. Conclusions: Short course therapy protocol may be a practical, simple approach for antibiotic use; it decreases hospital stays, eliminates delayed procedure times, lowers the economic cost of antimicrobials and lessens the chance of superinfection with and spread of antimicrobial resistant microorganisms. © 2012 Sayin Kutlu et al.
URI: https://hdl.handle.net/11499/8693
ISSN: 2036-6590
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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