Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8712
Title: Intracranial chondrosarcoma in a 22-years old Woman: Report of a case
Other Titles: Olgu Sunumu: 22 yaşında kadında i̇ntrakranial kondrosarkom
Authors: Altinboga, A.A.
Yalçın, Nagihan
Akbulut, Metin
Coşkun, Erdal
Düzcan, S. Ender
Keywords: Chondrosarcoma
Cranium
adult
article
cancer diagnosis
cancer surgery
case report
chondrosarcoma
female
follow up
histopathology
human
intracranial tumor
medical history
nuclear magnetic resonance imaging
rare disease
Abstract: Background: Intracranial chondroid tumors are consist of less than 0.16% of all primary brain neoplasms. They are classified as mesenchymal, classic and myxoid according to their cytoarchitecture. They usually arise at the skull base from the cartilaginous synchondroses and the pluripotent mesenchymal cells of the overlying dura mater. Case: We present a 22-year old female patient, who had history of seizures for 10 years and recent increase in the frequency of the seizures. Cranial magnetic resonance imaging (MRI) demonstrated a well-demarcated, parasagittal left frontal mass, which compressed to the lateral ventricle. It was hypointense on T1-weighted and hyperintense on T2-weighted images and making an edema on the surrounding tissue. Gross total resection of the firm mass was performed with clear margins. The tumor was composed of lobules of mature-appearing hyaline cartilage. The tumor cellularity was increased, each lacuna contained one or two atypical chondrocytes which had two or more nuclei per cell. Neoplastic chondrocytes had plump and hyperchromatic nuclei. Mitotic rate was low and no atypical mitotic figures were noted. Neoplastic chondrocytes showed nuclear staining for S-100 protein, but not for pancytokeratin. Histopathologic examination revealed a classic low grade chondrosarcoma. Conclusion: Intracranial chondrosarcomas are rare malign tumors. We report a patient with a grade I intracranial chondrosarcoma of the classical subtype without any neurologic problem after complete surgical excision. She did not received any adjuvant therapy and 28 months follow-up showed no recurrence. So it seems that, especially in the low grade chondrosarcoma, radical neurosurgical resection is the first line of treatment, and if necessary adjuvant therapy can be planned.
URI: https://hdl.handle.net/11499/8712
ISSN: 1300-1817
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Files in This Item:
File SizeFormat 
30118359-78b5-4846-994e-780420820823.pdf287.45 kBAdobe PDFView/Open
Show full item record



CORE Recommender

SCOPUSTM   
Citations

2
checked on Nov 30, 2024

WEB OF SCIENCETM
Citations

2
checked on Dec 4, 2024

Page view(s)

60
checked on Aug 24, 2024

Download(s)

20
checked on Aug 24, 2024

Google ScholarTM

Check





Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.