Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8752
Title: Testing of the excitability of a peripheral nerve in migraine patients
Authors: Erdogan, Çağdaş
Yücel, Mehmet
Degirmenci, Eylem
Akgün, H.
Öz, O.
Eroglu, E.
Odabaşi, Z.
Keywords: Migraine
Peripheral nerve excitability
Strength-duration time constant
adult
article
clinical article
controlled study
human
median nerve
migraine
nerve excitability
nerve stimulation
peripheral nerve
Publisher: Springer New York LLC
Abstract: Disorders in the functioning of ion channels, especially of Na+ channels, are at present suggested to play a role in the pathogenesis of migraine. Thus, migraine can be considered a channelopathy. The following question, however, remains open: Are such disorders related exclusively to the brain or also to the peripheral nervous system? In our study, we compared the excitability characteristics of the n. medianus in migraine patients and control-group subjects and also tried to find possible differences between subgroups of the patients suffering from migraine with or without aura. For this purpose, we measured the strength-duration time constant and rheobase using stimulation of the above nerve and EMG recording from the m. abductor pollicis brevis. We found no statistically significant differences in the indices of excitability of the peripheral nerve between the groups of control subjects and migraine patients and also between the above-mentioned subgroups of patients. © 2012 Springer Science+Business Media, Inc.
URI: https://hdl.handle.net/11499/8752
https://doi.org/10.1007/s11062-012-9233-9
ISSN: 0090-2977
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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