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https://hdl.handle.net/11499/8766
Title: | Elastic properties of the abdominal aorta in the children with bicuspid aortic valve: An observational study | Other Titles: | Biküspit aortik kapaklı çocuklarda abdominal aortun elastik özellikleri: Gözlemsel bir çalışma | Authors: | Gürses, Dolunay Özyürek, Arif Ruhi Levent, Reşit Ertürk Ülger Tutar, Zülal |
Keywords: | Abdominal aorta Aortic elasticity Bicuspid aortic valve Children Echocardiography Regression analysis abdominal aorta abdominal aorta diameter adolescent aorta valve regurgitation aortic strain arterial stiffness artery compliance article bicuspid aortic valve cardiovascular parameters child clinical article controlled study cross-sectional study diastolic blood pressure female human male observational study peak aortic velocity pressure strain elastic modulus pressure strain normalized by diastolic pressure school child systolic blood pressure transthoracic echocardiography aorta valve blood flow velocity case control study congenital heart malformation congenital malformation echocardiography echography elasticity pathophysiology regression analysis severity of illness index thoracic aorta Adolescent Aorta, Thoracic Aortic Valve Aortic Valve Insufficiency Blood Flow Velocity Case-Control Studies Child Cross-Sectional Studies Elasticity Female Heart Defects, Congenital Humans Male Regression Analysis Severity of Illness Index |
Publisher: | AVES Ibrahim Kara | Abstract: | Objective: Abnormalities of the aortic root and ascending aorta are common in patients with a bicuspid aortic valve (BAV). The aim of this study was to evaluate the stiffness of the abdominal aorta in children with BAV. Methods: In this cross-sectional observational study, we evaluated 35 children with normally functioning or mildly regurgitant BAV and 35 healthy children as controls. All children were noninvasively evaluated with transthoracic echocardiography. Annulus of aorta and abdominal aorta diameters were measured. Aortic strain (S), pressure strain elastic modulus (Ep), pressure strain normalized by diastolic pressure (Ep&z.ast;), aortic stiffness ß index (ßSI) and, aortic distensibility (DIS) were calculated using the measured data. In evaluation of the data Student's t-test, Chi-square test, Pearson's correlation and multivariate linear regression analysis were used. Results: Diameter of the aortic annulus was found significantly larger in the children with BAV than the control group (p<0.05). The abdominal aorta systolic and diastolic diameters were similar in the two groups (p>0.05). The children with BAV exhibited significantly lower S (0.210±0.04/0.267±0.07, p<0.001) and DIS (1.04±0.2/1.4±0.4 10-6 cm2 dyne-1, p<0.001); and higher Ep (200±39/153±47 N/m-2, p<0.001), Ep&z.ast; (3.42±0.9/2.5±0.9, p<0.001) and ßSI (1.1±0.3/0.84±0.3, p<0.001) than the control group. There was no correlation between the systolic and dia-stolic diameters of abdominal aorta and aortic elasticity parameters (p>0.05). Conclusion: Bicuspid aortic valve is associated with an increased abdominal aortic stiffness in children. However, impaired abdominal aortic elasticity is not due to abdominal aortic dilatation. These findings require validation by further studies. © 2012 by AVES Yayi{dotless}ni{dotless}li{dotless}k Ltd. | URI: | https://hdl.handle.net/11499/8766 https://doi.org/10.5152/akd.2012.125 |
ISSN: | 1302-8723 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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