Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/8920
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKhoueir, Z.-
dc.contributor.authorJassim, F.-
dc.contributor.authorPoon, L.Y.-C.-
dc.contributor.authorTsikata, E.-
dc.contributor.authorBen-David, G.S.-
dc.contributor.authorLiu, Y.-
dc.contributor.authorShieh, E.-
dc.date.accessioned2019-08-16T12:57:10Z-
dc.date.available2019-08-16T12:57:10Z-
dc.date.issued2017-
dc.identifier.issn0002-9394-
dc.identifier.urihttps://hdl.handle.net/11499/8920-
dc.identifier.urihttps://doi.org/10.1016/j.ajo.2017.08.001-
dc.description.abstractPurpose To determine the diagnostic capability of peripapillary 3-dimensional (3D) retinal nerve fiber layer (RNFL) volume measurements from spectral-domain optical coherence tomography (OCT) volume scans for open-angle glaucoma (OAG). Design Assessment of diagnostic accuracy. Methods SETTING: Academic clinical setting. STUDY POPULATION: Total of 180 patients (113 OAG and 67 normal subjects). OBSERVATION PROCEDURES: One eye per subject was included. Peripapillary 3D RNFL volumes were calculated for global, quadrant, and sector regions, using 4 different-size annuli. Peripapillary 2D RNFL thickness circle scans were also obtained. MAIN OUTCOME MEASURES: Area under the receiver operating characteristic curve (AUROC) values, sensitivity, specificity, positive and negative predictive values, positive and negative likelihood ratios. Results Among all 2D and 3D RNFL parameters, best diagnostic capability was associated with inferior quadrant 3D RNFL volume of the smallest annulus (AUROC value 0.977). Otherwise, global 3D RNFL volume AUROC values were comparable to global 2D RNFL thickness AUROC values for all 4 annulus sizes (P values:.0593 to.6866). When comparing the 4 annulus sizes for global RNFL volume, the smallest annulus had the best AUROC values (P values:.0317 to.0380). The smallest-size annulus may have the best diagnostic potential, partly owing to having no areas excluded for being larger than the 6 × 6 mm2 scanned region. Conclusion Peripapillary 3D RNFL volume showed excellent diagnostic performance for detecting glaucoma. Peripapillary 3D RNFL volume parameters have the same or better diagnostic capability compared to peripapillary 2D RNFL thickness measurements, although differences were not statistically significant. © 2017 Elsevier Inc.en_US
dc.language.isoenen_US
dc.publisherElsevier Inc.en_US
dc.relation.ispartofAmerican Journal of Ophthalmologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectadulten_US
dc.subjectageden_US
dc.subjectArticleen_US
dc.subjectcontrolled studyen_US
dc.subjectdiagnostic accuracyen_US
dc.subjectdiagnostic test accuracy studyen_US
dc.subjectdiagnostic valueen_US
dc.subjecthumanen_US
dc.subjectintermethod comparisonen_US
dc.subjectmajor clinical studyen_US
dc.subjectmiddle ageden_US
dc.subjectopen angle glaucomaen_US
dc.subjectoptical coherence tomography deviceen_US
dc.subjectoutcome assessmenten_US
dc.subjectpredictive valueen_US
dc.subjectpriority journalen_US
dc.subjectreceiver operating characteristicen_US
dc.subjectretinal nerve fiber layer thicknessen_US
dc.subjectsensitivity and specificityen_US
dc.subjectspectral domain optical coherence tomographyen_US
dc.subjectthree dimensional imagingen_US
dc.subjecttwo-dimensional imagingen_US
dc.subjectarea under the curveen_US
dc.subjectcross-sectional studyen_US
dc.subjectfalse negative resulten_US
dc.subjectfemaleen_US
dc.subjectGlaucoma, Open-Angleen_US
dc.subjectintraocular pressureen_US
dc.subjectmaleen_US
dc.subjectnerve fiberen_US
dc.subjectoptic disken_US
dc.subjectoptical coherence tomographyen_US
dc.subjectpathologyen_US
dc.subjectperimetryen_US
dc.subjectphysiologyen_US
dc.subjectproceduresen_US
dc.subjectreproducibilityen_US
dc.subjectretina ganglion cellen_US
dc.subjectstandardsen_US
dc.subjectvisual fielden_US
dc.subjectAgeden_US
dc.subjectArea Under Curveen_US
dc.subjectCross-Sectional Studiesen_US
dc.subjectFalse Negative Reactionsen_US
dc.subjectFemaleen_US
dc.subjectHumansen_US
dc.subjectImaging, Three-Dimensionalen_US
dc.subjectIntraocular Pressureen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectNerve Fibersen_US
dc.subjectOptic Disken_US
dc.subjectPredictive Value of Testsen_US
dc.subjectReproducibility of Resultsen_US
dc.subjectRetinal Ganglion Cellsen_US
dc.subjectROC Curveen_US
dc.subjectSensitivity and Specificityen_US
dc.subjectTomography, Optical Coherenceen_US
dc.subjectVisual Field Testsen_US
dc.subjectVisual Fieldsen_US
dc.titleDiagnostic Capability of Peripapillary Three-dimensional Retinal Nerve Fiber Layer Volume for Glaucoma Using Optical Coherence Tomography Volume Scansen_US
dc.typeArticleen_US
dc.identifier.volume182en_US
dc.identifier.startpage180
dc.identifier.startpage180en_US
dc.identifier.endpage193en_US
dc.identifier.doi10.1016/j.ajo.2017.08.001-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid28807732en_US
dc.identifier.scopus2-s2.0-85028638490en_US
dc.identifier.wosWOS:000411920900023en_US
dc.identifier.scopusqualityQ1-
dc.ownerPamukkale University-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
item.fulltextWith Fulltext-
item.languageiso639-1en-
item.grantfulltextopen-
item.cerifentitytypePublications-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Files in This Item:
File SizeFormat 
nihms904323.pdf777.49 kBAdobe PDFView/Open
Show simple item record



CORE Recommender

SCOPUSTM   
Citations

13
checked on Nov 16, 2024

WEB OF SCIENCETM
Citations

12
checked on Nov 21, 2024

Page view(s)

42
checked on Aug 24, 2024

Download(s)

18
checked on Aug 24, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.