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https://hdl.handle.net/11499/8920
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DC Field | Value | Language |
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dc.contributor.author | Khoueir, Z. | - |
dc.contributor.author | Jassim, F. | - |
dc.contributor.author | Poon, L.Y.-C. | - |
dc.contributor.author | Tsikata, E. | - |
dc.contributor.author | Ben-David, G.S. | - |
dc.contributor.author | Liu, Y. | - |
dc.contributor.author | Shieh, E. | - |
dc.date.accessioned | 2019-08-16T12:57:10Z | - |
dc.date.available | 2019-08-16T12:57:10Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0002-9394 | - |
dc.identifier.uri | https://hdl.handle.net/11499/8920 | - |
dc.identifier.uri | https://doi.org/10.1016/j.ajo.2017.08.001 | - |
dc.description.abstract | Purpose To determine the diagnostic capability of peripapillary 3-dimensional (3D) retinal nerve fiber layer (RNFL) volume measurements from spectral-domain optical coherence tomography (OCT) volume scans for open-angle glaucoma (OAG). Design Assessment of diagnostic accuracy. Methods SETTING: Academic clinical setting. STUDY POPULATION: Total of 180 patients (113 OAG and 67 normal subjects). OBSERVATION PROCEDURES: One eye per subject was included. Peripapillary 3D RNFL volumes were calculated for global, quadrant, and sector regions, using 4 different-size annuli. Peripapillary 2D RNFL thickness circle scans were also obtained. MAIN OUTCOME MEASURES: Area under the receiver operating characteristic curve (AUROC) values, sensitivity, specificity, positive and negative predictive values, positive and negative likelihood ratios. Results Among all 2D and 3D RNFL parameters, best diagnostic capability was associated with inferior quadrant 3D RNFL volume of the smallest annulus (AUROC value 0.977). Otherwise, global 3D RNFL volume AUROC values were comparable to global 2D RNFL thickness AUROC values for all 4 annulus sizes (P values:.0593 to.6866). When comparing the 4 annulus sizes for global RNFL volume, the smallest annulus had the best AUROC values (P values:.0317 to.0380). The smallest-size annulus may have the best diagnostic potential, partly owing to having no areas excluded for being larger than the 6 × 6 mm2 scanned region. Conclusion Peripapillary 3D RNFL volume showed excellent diagnostic performance for detecting glaucoma. Peripapillary 3D RNFL volume parameters have the same or better diagnostic capability compared to peripapillary 2D RNFL thickness measurements, although differences were not statistically significant. © 2017 Elsevier Inc. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Inc. | en_US |
dc.relation.ispartof | American Journal of Ophthalmology | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | adult | en_US |
dc.subject | aged | en_US |
dc.subject | Article | en_US |
dc.subject | controlled study | en_US |
dc.subject | diagnostic accuracy | en_US |
dc.subject | diagnostic test accuracy study | en_US |
dc.subject | diagnostic value | en_US |
dc.subject | human | en_US |
dc.subject | intermethod comparison | en_US |
dc.subject | major clinical study | en_US |
dc.subject | middle aged | en_US |
dc.subject | open angle glaucoma | en_US |
dc.subject | optical coherence tomography device | en_US |
dc.subject | outcome assessment | en_US |
dc.subject | predictive value | en_US |
dc.subject | priority journal | en_US |
dc.subject | receiver operating characteristic | en_US |
dc.subject | retinal nerve fiber layer thickness | en_US |
dc.subject | sensitivity and specificity | en_US |
dc.subject | spectral domain optical coherence tomography | en_US |
dc.subject | three dimensional imaging | en_US |
dc.subject | two-dimensional imaging | en_US |
dc.subject | area under the curve | en_US |
dc.subject | cross-sectional study | en_US |
dc.subject | false negative result | en_US |
dc.subject | female | en_US |
dc.subject | Glaucoma, Open-Angle | en_US |
dc.subject | intraocular pressure | en_US |
dc.subject | male | en_US |
dc.subject | nerve fiber | en_US |
dc.subject | optic disk | en_US |
dc.subject | optical coherence tomography | en_US |
dc.subject | pathology | en_US |
dc.subject | perimetry | en_US |
dc.subject | physiology | en_US |
dc.subject | procedures | en_US |
dc.subject | reproducibility | en_US |
dc.subject | retina ganglion cell | en_US |
dc.subject | standards | en_US |
dc.subject | visual field | en_US |
dc.subject | Aged | en_US |
dc.subject | Area Under Curve | en_US |
dc.subject | Cross-Sectional Studies | en_US |
dc.subject | False Negative Reactions | en_US |
dc.subject | Female | en_US |
dc.subject | Humans | en_US |
dc.subject | Imaging, Three-Dimensional | en_US |
dc.subject | Intraocular Pressure | en_US |
dc.subject | Male | en_US |
dc.subject | Middle Aged | en_US |
dc.subject | Nerve Fibers | en_US |
dc.subject | Optic Disk | en_US |
dc.subject | Predictive Value of Tests | en_US |
dc.subject | Reproducibility of Results | en_US |
dc.subject | Retinal Ganglion Cells | en_US |
dc.subject | ROC Curve | en_US |
dc.subject | Sensitivity and Specificity | en_US |
dc.subject | Tomography, Optical Coherence | en_US |
dc.subject | Visual Field Tests | en_US |
dc.subject | Visual Fields | en_US |
dc.title | Diagnostic Capability of Peripapillary Three-dimensional Retinal Nerve Fiber Layer Volume for Glaucoma Using Optical Coherence Tomography Volume Scans | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 182 | en_US |
dc.identifier.startpage | 180 | |
dc.identifier.startpage | 180 | en_US |
dc.identifier.endpage | 193 | en_US |
dc.identifier.doi | 10.1016/j.ajo.2017.08.001 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 28807732 | en_US |
dc.identifier.scopus | 2-s2.0-85028638490 | en_US |
dc.identifier.wos | WOS:000411920900023 | en_US |
dc.identifier.scopusquality | Q1 | - |
dc.owner | Pamukkale University | - |
item.languageiso639-1 | en | - |
item.fulltext | With Fulltext | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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