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https://hdl.handle.net/11499/9082
Title: | Comparison of ganglion cell and retinal nerve fiber layer thickness in pigment dispersion syndrome, pigmentary glaucoma, and healthy subjects with spectral-domain OCT | Authors: | Arifoglu, H.B. Simavli, H. Midillioglu, I. Berk Ergun, S. Simsek, S. |
Keywords: | Ganglion cell layer optical coherence tomography pigment dispersion pigmentary glaucoma retinal nerve fiber layer abnormal value adult Article best corrected visual acuity clinical evaluation comparative study controlled clinical trial controlled study cross-sectional study diagnostic test accuracy study diagnostic value eye disease female glaucoma Goldmann applanation tonometer gonioscopy human Humphrey perimeter major clinical study male optical coherence tomography device pigment dispersion syndrome post hoc analysis priority journal prospective study retina ganglion cell retinal nerve fiber layer thickness slit lamp slit lamp microscopy spectral domain optical coherence tomography stereoscopic vision visual field visual field defect visual field laser instrument Glaucoma, Open-Angle middle aged nerve fiber normal human pathology procedures retinal pigment epithelium Adult Cross-Sectional Studies Female Healthy Volunteers Humans Male Middle Aged Nerve Fibers Prospective Studies Retinal Ganglion Cells Retinal Pigment Epithelium Tomography, Optical Coherence |
Publisher: | Taylor and Francis Ltd | Abstract: | Purpose: To evaluate the ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL) thickness in pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG) with RTVue spectral domain optical coherence tomography (SD-OCT). Methods: A total of 102 subjects were enrolled: 29 with PDS, 18 with PG, and 55 normal subjects. Full ophthalmic examination including visual field analysis was performed. SD-OCT was used to analyze GCC superior, GCC inferior, and average RNFL thickness. To compare the discrimination capabilities, the areas under the receiver operating characteristic curves were assessed. Results: Superior GCC, inferior GCC, and RNFL thickness values of patients with PG were statistically signicantly lower than those of patients with PDS (p < 0.001) and healthy individuals (p < 0.001 for all). No statistically significant difference was found between PDS and normal subjects in same parameters (p > 0.05). Conclusions: The SD-OCT-derived GCC and RNFL thickness parameters can be useful to discriminate PG from both PDS and normal subjects. © Taylor & Francis. | URI: | https://hdl.handle.net/11499/9082 https://doi.org/10.3109/08820538.2015.1053623 |
ISSN: | 0882-0538 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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