Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/9082
Title: Comparison of ganglion cell and retinal nerve fiber layer thickness in pigment dispersion syndrome, pigmentary glaucoma, and healthy subjects with spectral-domain OCT
Authors: Arifoglu, H.B.
Simavli, H.
Midillioglu, I.
Berk Ergun, S.
Simsek, S.
Keywords: Ganglion cell layer
optical coherence tomography
pigment dispersion
pigmentary glaucoma
retinal nerve fiber layer
abnormal value
adult
Article
best corrected visual acuity
clinical evaluation
comparative study
controlled clinical trial
controlled study
cross-sectional study
diagnostic test accuracy study
diagnostic value
eye disease
female
glaucoma
Goldmann applanation tonometer
gonioscopy
human
Humphrey perimeter
major clinical study
male
optical coherence tomography device
pigment dispersion syndrome
post hoc analysis
priority journal
prospective study
retina ganglion cell
retinal nerve fiber layer thickness
slit lamp
slit lamp microscopy
spectral domain optical coherence tomography
stereoscopic vision
visual field
visual field defect
visual field laser instrument
Glaucoma, Open-Angle
middle aged
nerve fiber
normal human
pathology
procedures
retinal pigment epithelium
Adult
Cross-Sectional Studies
Female
Healthy Volunteers
Humans
Male
Middle Aged
Nerve Fibers
Prospective Studies
Retinal Ganglion Cells
Retinal Pigment Epithelium
Tomography, Optical Coherence
Publisher: Taylor and Francis Ltd
Abstract: Purpose: To evaluate the ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL) thickness in pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG) with RTVue spectral domain optical coherence tomography (SD-OCT). Methods: A total of 102 subjects were enrolled: 29 with PDS, 18 with PG, and 55 normal subjects. Full ophthalmic examination including visual field analysis was performed. SD-OCT was used to analyze GCC superior, GCC inferior, and average RNFL thickness. To compare the discrimination capabilities, the areas under the receiver operating characteristic curves were assessed. Results: Superior GCC, inferior GCC, and RNFL thickness values of patients with PG were statistically signicantly lower than those of patients with PDS (p < 0.001) and healthy individuals (p < 0.001 for all). No statistically significant difference was found between PDS and normal subjects in same parameters (p > 0.05). Conclusions: The SD-OCT-derived GCC and RNFL thickness parameters can be useful to discriminate PG from both PDS and normal subjects. © Taylor & Francis.
URI: https://hdl.handle.net/11499/9082
https://doi.org/10.3109/08820538.2015.1053623
ISSN: 0882-0538
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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