Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/9104
Full metadata record
DC FieldValueLanguage
dc.contributor.authorDemiray, Gökçen-
dc.contributor.authorDeğirmencioğlu, Serkan-
dc.contributor.authorUğurlu, Erhan-
dc.contributor.authorYaren, Arzu-
dc.date.accessioned2019-08-16T12:58:21Z-
dc.date.available2019-08-16T12:58:21Z-
dc.date.issued2017-
dc.identifier.issn1179-5549-
dc.identifier.urihttps://hdl.handle.net/11499/9104-
dc.identifier.urihttps://doi.org/10.1177/1179554917690144-
dc.description.abstractIntr oducti on: Cancer cachexia is one of the most frequent effects of malignancy, is often associated with poor prognosis, and may account for up to 20% of cancer deaths. The aim of our study was to evaluate the relationship of cancer cachexia and serum levels of resistin and leptin in patients with advanced non-small cell lung cancer. Met hods: A total of 67 chemotherapy-naïve patients with advanced-stage non-small cell cancer and a control group containing 20 healthy individuals without a known chronic disease were enrolled in this study. All individuals in the control group were age and sex matched. Demographic, anthropometric, laboratory data and serum levels of adipokines were measured for 2 groups. Progression-free survival and overall survival were estimated using the Kaplan-Meier method. Survival among various factors was calculated using the log-rank test. Res ults : Patients presented significantly higher serum resistin (P =.0001) and lower serum leptin levels (P =.025) than the control group. Lower serum levels of leptin were correlated with overall survival (P =.011). Concl usi ons : Serum leptin and resistin levels play key role as proinflammatory cytokines in lung cancer and cancer cachexia; however, their use as diagnostic or prognostic markers is not possible yet, and further large-scale studies are required to confirm our findings. © The Author(s) 2017.en_US
dc.language.isoenen_US
dc.publisherLibertas Academica Ltd.en_US
dc.relation.ispartofClinical Medicine Insights: Oncologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCancer cachexiaen_US
dc.subjectLeptinen_US
dc.subjectLung canceren_US
dc.subjectResistinen_US
dc.subjectadipocytokineen_US
dc.subjectadiponectinen_US
dc.subjectalbuminen_US
dc.subjectC reactive proteinen_US
dc.subjecthemoglobinen_US
dc.subjectlactate dehydrogenaseen_US
dc.subjectleptinen_US
dc.subjectresistinen_US
dc.subjectadulten_US
dc.subjectadvanced canceren_US
dc.subjectanemiaen_US
dc.subjectanthropometric parametersen_US
dc.subjectarm circumferenceen_US
dc.subjectArticleen_US
dc.subjectblood samplingen_US
dc.subjectbody massen_US
dc.subjectbody weighten_US
dc.subjectcachexiaen_US
dc.subjectcancer mortalityen_US
dc.subjectcancer prognosisen_US
dc.subjectcancer stagingen_US
dc.subjectcancer survivalen_US
dc.subjectchronic diseaseen_US
dc.subjectcomorbidityen_US
dc.subjectcontrolled studyen_US
dc.subjectfemaleen_US
dc.subjecthip circumferenceen_US
dc.subjecthumanen_US
dc.subjectmajor clinical studyen_US
dc.subjectmaleen_US
dc.subjectmuscle thicknessen_US
dc.subjectnon small cell lung canceren_US
dc.subjectoverall survivalen_US
dc.subjectprogression free survivalen_US
dc.subjectprotein blood levelen_US
dc.subjectquality of lifeen_US
dc.subjectsmokingen_US
dc.subjecttriceps brachii muscleen_US
dc.subjectwaist circumferenceen_US
dc.subjectwaist hip ratioen_US
dc.subjectweight reductionen_US
dc.titleEffects of serum leptin and resistin levels on cancer cachexia in patients with advanced-stage non-small cell lung canceren_US
dc.typeArticleen_US
dc.identifier.volume11en_US
dc.authorid0000-0002-1213-2778-
dc.authorid0000-00015402-6925-
dc.identifier.doi10.1177/1179554917690144-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid28469508en_US
dc.identifier.scopus2-s2.0-85016154142en_US
dc.identifier.wosWOS:000397768400001en_US
dc.identifier.scopusqualityQ2-
dc.ownerPamukkale University-
item.languageiso639-1en-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.openairetypeArticle-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Files in This Item:
File SizeFormat 
10.1177 1179554917690144.pdf134.83 kBAdobe PDFView/Open
Show simple item record



CORE Recommender

SCOPUSTM   
Citations

35
checked on Nov 30, 2024

WEB OF SCIENCETM
Citations

32
checked on Dec 2, 2024

Page view(s)

56
checked on Aug 24, 2024

Download(s)

52
checked on Aug 24, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.