Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/9262
Title: Visual, topographic, and pachymetric effects of pediatric corneal collagen cross-linking
Authors: Toprak, İbrahim
Yaylalı, Volkan
Yıldırım, Cem
Keywords: isotonic solution
riboflavin
collagen
cross linking reagent
adolescent
anterior eye chamber angle
anterior eye chamber depth
Article
child
clinical article
cornea surgery
corneal collagen cross linking
corneal pachymetry
corrected distance visual acuity
female
follow up
human
keratoconus
keratometry
male
outcome assessment
pediatrics
surgical technique
ultraviolet A radiation
cornea
pathology
photochemotherapy
procedures
retrospective study
time factor
visual acuity
Adolescent
Child
Collagen
Cornea
Corneal Pachymetry
Corneal Topography
Cross-Linking Reagents
Female
Follow-Up Studies
Humans
Keratoconus
Male
Photochemotherapy
Retrospective Studies
Time Factors
Visual Acuity
Publisher: Slack Incorporated
Abstract: Purpose: To evaluate the effects of pediatric corneal collagen cross-linking (CXL) on corrected distance visual acuity (CDVA), maximum keratometry (Kmax), and other Scheimpflug imaging system parameters during 2 years of follow-up. Methods: The records of 29 eyes of 29 pediatric patients who underwent unilateral CXL treatment for progressive keratoconus were reviewed. Changes in CDVA, Kmax, anterior chamber depth, anterior chamber volume, anterior chamber angle, pupil-center pachymetry, apical pachymetry, thinnest pachymetry, corneal volume, and topographic indices (index of surface variance [ISV], index of vertical asymmetry [IVA], index of height asymmetry [IHA], keratoconus index [KI], center keratoconus index [CKI], index of height decentration [IHD], and minimum radius of curvature [Rmin]) were analyzed among baseline and 1 and 2 years after the CXL treatment. Results: Mean CDVA and Kmax significantly improved from baseline at 1 year (-0.17 logMAR, P < .0001; -1.18 diopters [D], P = .012, respectively) and 2 years (-0.21 logMAR, P < .0001; -1.40 D, P = .001, respectively) after the CXL treatment. Anterior chamber parameters, corneal thicknesses, and corneal volume remained unchanged during the period following CXL (P > .05). Five of the seven Scheimpflug topographic indices (including ISV, KI, CKI, IHD, and Rmin) showed significant improvement after CXL between baseline and 2 years (P < .05). Conclusions: In pediatric patients with progressive keratoconus, CXL appears to be effective in improving CDVA, Kmax, and corneal topographic irregularity at 2 years' follow-up. However, long-term effects of CXL should be tested by further studies in pediatric keratoconus.
URI: https://hdl.handle.net/11499/9262
https://doi.org/10.3928/01913913-20160831-01
ISSN: 0191-3913
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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