Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/9386
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yaylalı, Yalın Tolga | - |
dc.contributor.author | Saricopur, Ahmet | - |
dc.contributor.author | Yurtdas, M. | - |
dc.contributor.author | Şenol, Hande | - |
dc.contributor.author | Gokoz-Dogu, G. | - |
dc.date.accessioned | 2019-08-16T13:00:35Z | - |
dc.date.available | 2019-08-16T13:00:35Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0066-782X | - |
dc.identifier.uri | https://hdl.handle.net/11499/9386 | - |
dc.identifier.uri | https://doi.org/10.5935/abc.20160146 | - |
dc.description.abstract | Background: Atrial electromechanical delay (EMD) is used to predict atrial fibrillation, measured by echocardiography. Objectives: The aim of this study was to assess atrial EMD and mechanical function after anthracycline-containing chemotherapy. Methods: Fifty-three patients with breast cancer (48 ± 8 years old) who received 240 mg/m2of Adriamycin, 2400 mg/m2 of cyclophosphamide, and 960 mg/m2 of paclitaxel were included in this retrospective study, as were 42 healthy subjects (47 ± 9 years old). Echocardiographic measurements were performed 11 ± 7 months (median 9 months) after treatment with anthracyclines. Results: Left intra-atrial EMD (11.4 ± 6.0 vs. 8.1 ± 4.9, p=0.008) and inter-atrial EMD (19.7 ± 7.4 vs. 14.7 ± 6.5, p=0.001) were prolonged; LA passive emptying volume and fraction were decreased (p=0.0001 and p=0.0001); LA active emptying volume and fraction were increased (p=0.0001 and p=0.0001); Mitral A velocity (0.8 ± 0.2 vs. 0.6 ± 0.2, p=0.0001) and mitral E-wave deceleration time (201.2 ± 35.6 vs. 163.7 ± 21.8, p=0.0001) were increased; Mitral E/A ratio (1.0 ± 0.3 vs. 1.3 ± 0.3, p=0.0001) and mitral Em (0.09 ± 0.03 vs. 0.11 ± 0.03, p=0.001) were decreased; Mitral Am (0.11 ± 0.02 vs. 0.09 ± 0.02, p=0.0001) and mitral E/Em ratio (8.8 ± 3.2 vs. 7.6 ± 2.6, p=0.017) were increased in the patients. Conclusions: In patients with breast cancer after anthracycline therapy: Left intra-atrial, inter-atrial electromechanical intervals were prolonged. Diastolic function was impaired. Impaired left ventricular relaxation and left atrial electrical conduction could be contributing to the development of atrial arrhythmias. © 2016, Arquivos Brasileiros de Cardiologia. All rights reserved. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Arquivos Brasileiros de Cardiologia | en_US |
dc.relation.ispartof | Arquivos Brasileiros de Cardiologia | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Antrhacyclines | en_US |
dc.subject | Arrhythmias, cardiac | en_US |
dc.subject | Atrial function | en_US |
dc.subject | Cardiotoxicity | en_US |
dc.subject | Drug therapy | en_US |
dc.subject | Unilateral breast neoplasms | en_US |
dc.subject | cyclophosphamide | en_US |
dc.subject | doxorubicin | en_US |
dc.subject | paclitaxel | en_US |
dc.subject | anthracycline | en_US |
dc.subject | antineoplastic agent | en_US |
dc.subject | adult | en_US |
dc.subject | aged | en_US |
dc.subject | Article | en_US |
dc.subject | atrial fibrillation | en_US |
dc.subject | breast cancer | en_US |
dc.subject | cancer chemotherapy | en_US |
dc.subject | controlled study | en_US |
dc.subject | diastolic blood pressure | en_US |
dc.subject | excitation contraction coupling | en_US |
dc.subject | female | en_US |
dc.subject | heart arrhythmia | en_US |
dc.subject | heart atrium function | en_US |
dc.subject | heart left ventricle ejection fraction | en_US |
dc.subject | heart rate | en_US |
dc.subject | human | en_US |
dc.subject | major clinical study | en_US |
dc.subject | maximum reaction velocity | en_US |
dc.subject | retrospective study | en_US |
dc.subject | systolic blood pressure | en_US |
dc.subject | transthoracic echocardiography | en_US |
dc.subject | Arrhythmias, Cardiac | en_US |
dc.subject | blood pressure | en_US |
dc.subject | Breast Neoplasms | en_US |
dc.subject | case control study | en_US |
dc.subject | diastole | en_US |
dc.subject | echocardiography | en_US |
dc.subject | heart left ventricle function | en_US |
dc.subject | middle aged | en_US |
dc.subject | pathophysiology | en_US |
dc.subject | physiology | en_US |
dc.subject | predictive value | en_US |
dc.subject | systole | en_US |
dc.subject | Adult | en_US |
dc.subject | Anthracyclines | en_US |
dc.subject | Antineoplastic Combined Chemotherapy Protocols | en_US |
dc.subject | Atrial Fibrillation | en_US |
dc.subject | Blood Pressure | en_US |
dc.subject | Case-Control Studies | en_US |
dc.subject | Cyclophosphamide | en_US |
dc.subject | Diastole | en_US |
dc.subject | Doxorubicin | en_US |
dc.subject | Echocardiography | en_US |
dc.subject | Female | en_US |
dc.subject | Humans | en_US |
dc.subject | Middle Aged | en_US |
dc.subject | Paclitaxel | en_US |
dc.subject | Predictive Value of Tests | en_US |
dc.subject | Retrospective Studies | en_US |
dc.subject | Systole | en_US |
dc.subject | Ventricular Dysfunction, Left | en_US |
dc.subject | Ventricular Function, Left | en_US |
dc.title | Atrial function in patients with breast cancer after treatment with anthracyclines | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 107 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 411 | - |
dc.identifier.startpage | 411 | en_US |
dc.identifier.endpage | 419 | en_US |
dc.identifier.doi | 10.5935/abc.20160146 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 27812678 | en_US |
dc.identifier.scopus | 2-s2.0-84994666665 | en_US |
dc.identifier.wos | WOS:000391430900003 | en_US |
dc.identifier.scopusquality | Q3 | - |
dc.owner | Pamukkale University | - |
item.languageiso639-1 | en | - |
item.fulltext | With Fulltext | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
Files in This Item:
File | Size | Format | |
---|---|---|---|
Interativa_portugues.pdf | 4.83 MB | Adobe PDF | View/Open |
CORE Recommender
SCOPUSTM
Citations
16
checked on Oct 13, 2024
WEB OF SCIENCETM
Citations
16
checked on Oct 31, 2024
Page view(s)
60
checked on Aug 24, 2024
Download(s)
140
checked on Aug 24, 2024
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.