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https://hdl.handle.net/11499/9442
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Serinken, Mustafa | - |
dc.contributor.author | Eken, C. | - |
dc.contributor.author | Elicabuk, H. | - |
dc.date.accessioned | 2019-08-16T13:01:31Z | |
dc.date.available | 2019-08-16T13:01:31Z | |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1071-1007 | - |
dc.identifier.uri | https://hdl.handle.net/11499/9442 | - |
dc.identifier.uri | https://doi.org/10.1177/1071100716650530 | - |
dc.description.abstract | Background: Topical agents have been shown to be effective in soft tissue injuries and commonly used in outpatient clinics. However, the data regarding topical agents in the emergency department is insufficient, and they are not used often in the emergency department setting. The present study aimed to compare the effect of 2.5% topical ketoprofen (gel form) to placebo in patients presenting with ankle sprain to the emergency department. Methods: Patients presenting with ankle sprain composed the study population. Study patients were randomized into 2 study arms: 2.5% ketoprofen gel and placebo administered over a 5-cm area locally. Pain alleviation was measured by visual analog scale at 15 and 30 minutes. A total of 100 patients were included in the final analysis. Results: The median pain reduction in ketoprofen and placebo groups at 15 minutes was 27 (19.8-33.4) and 9 (7.6-17), respectively. The median pain reduction at 30 minutes for both groups was 42 (36-50.8) and 20 (17.6-24.4), respectively. Pain improvement either at 15 minutes (median difference: 16 [9-22]) or 30 minutes (median difference: 21 [15-27]) was better in the ketoprofen group than placebo. There were no adverse effects in either group. Conclusion: Ketoprofen gel was superior to placebo at 30 minutes in alleviating pain secondary to ankle sprain in the ED with a high safety profile. Further studies are needed concerning the effect of ketoprofen gel for long-term effects. Level of Evidence: Level I, high quality prospective randomized study. © The Author(s) 2016. | en_US |
dc.language.iso | en | en_US |
dc.publisher | SAGE Publications Inc. | en_US |
dc.relation.ispartof | Foot and Ankle International | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | ankle sprain | en_US |
dc.subject | emergency department | en_US |
dc.subject | ketoprofen | en_US |
dc.subject | topical | en_US |
dc.subject | placebo | en_US |
dc.subject | ketoprofen topical gel | en_US |
dc.subject | nonsteroid antiinflammatory agent | en_US |
dc.subject | absence of side effects | en_US |
dc.subject | adult | en_US |
dc.subject | Article | en_US |
dc.subject | comparative effectiveness | en_US |
dc.subject | controlled clinical trial | en_US |
dc.subject | controlled study | en_US |
dc.subject | double blind procedure | en_US |
dc.subject | emergency ward | en_US |
dc.subject | female | en_US |
dc.subject | gel | en_US |
dc.subject | human | en_US |
dc.subject | intention to treat analysis | en_US |
dc.subject | major clinical study | en_US |
dc.subject | male | en_US |
dc.subject | pain intensity | en_US |
dc.subject | pain measurement | en_US |
dc.subject | priority journal | en_US |
dc.subject | prospective study | en_US |
dc.subject | topical treatment | en_US |
dc.subject | visual analog scale | en_US |
dc.subject | analogs and derivatives | en_US |
dc.subject | Ankle Injuries | en_US |
dc.subject | hospital emergency service | en_US |
dc.subject | pain | en_US |
dc.subject | Sprains and Strains | en_US |
dc.subject | treatment outcome | en_US |
dc.subject | Anti-Inflammatory Agents, Non-Steroidal | en_US |
dc.subject | Double-Blind Method | en_US |
dc.subject | Emergency Service, Hospital | en_US |
dc.subject | Humans | en_US |
dc.subject | Ketoprofen | en_US |
dc.subject | Pain | en_US |
dc.subject | Pain Measurement | en_US |
dc.subject | Prospective Studies | en_US |
dc.subject | Treatment Outcome | en_US |
dc.title | Topical ketoprofen versus placebo in treatment of acute ankle sprain in the emergency department | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 37 | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.startpage | 989 | |
dc.identifier.startpage | 989 | en_US |
dc.identifier.endpage | 993 | en_US |
dc.identifier.doi | 10.1177/1071100716650530 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 27198132 | en_US |
dc.identifier.scopus | 2-s2.0-84986218222 | en_US |
dc.identifier.wos | WOS:000382971600012 | en_US |
dc.identifier.scopusquality | Q1 | - |
dc.owner | Pamukkale University | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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