Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/9642
Title: Is high pressure postdilation safe in bioresorbable vascular scaffolds? Optical coherence tomography observations after noncompliant balloons inflated at more than 24 atmospheres
Authors: Fabris, E.
Caiazzo, G.
Kılıç, İsmail Doğu
Serdoz, R.
Secco, G.G.
Sinagra, G.
Lee, R.
Keywords: bioresorbable vascular scaffolds
coronary angioplasty
noncompliant balloon
optical coherence tomography
struts apposition
adult
Article
balloon
bioresorbable scaffold
clinical article
cohort analysis
controlled study
drug eluting stent
eccentricity index
edge dissection
female
high pressure postdilation
human
in vivo study
incomplete strut apposition
male
medical device complication
optical coherence tomography device
physical parameters
pressure and tension
residual area stenosis
stent fracture
stent malapposition
symmetry index
tissue prolapse
adverse effects
aged
biodegradable implant
coronary artery disease
coronary blood vessel
diagnostic imaging
heart catheter
mechanical stress
middle aged
predictive value
pressure
procedures
prosthesis complication
prosthesis design
risk factor
time factor
transluminal coronary angioplasty
treatment outcome
biocompatible coated material
cardiovascular agent
Absorbable Implants
Aged
Angioplasty, Balloon, Coronary
Cardiac Catheters
Cardiovascular Agents
Coated Materials, Biocompatible
Coronary Artery Disease
Coronary Vessels
Female
Humans
Male
Middle Aged
Predictive Value of Tests
Pressure
Prosthesis Design
Prosthesis Failure
Risk Factors
Stress, Mechanical
Time Factors
Tomography, Optical Coherence
Treatment Outcome
Publisher: John Wiley and Sons Inc.
Abstract: Objectives Optical coherence tomography (OCT) was used to investigate integrity and expansion of bioresorbable drug-eluting scaffolds (BVS) after high-pressure postdilation (HPPD). Background Because of concerns about the risk of BVS damage, postdilation was not recommended and applied in the existing randomized studies and most registries. Recent real world data suggest incomplete BVS expansion cause higher rates of thrombosis. In vivo confirmation of the safety of high pressure postdilation is of paramount importance. Methods Data from final OCT examination of consecutive implanted BVS, postdilated with noncompliant (NC) balloons at pressure ?24 atm were analyzed. The following stent performance indices were assessed with OCT: mean and minimal lumen and scaffold area, residual area stenosis (RAS), incomplete strut apposition (ISA), tissue prolapse, eccentricity index (EI), symmetry index (SI), strut fractures, and edge dissections. Result Twenty-two BVS postdilated at high pressure were analyzed. The average maximal postdilation balloon inflation (maxPD) was 28 ± 3 atm. High pressure OPN NC Balloon (SIS Medical AG, Winterthur Switzerland) was used in 41% of postdilations with a maximal PD of 30 ± 4.7 atm. Final mean and minimal lumen area were 6.8 ± 1.4 and 5.5 ± 1.4 mm2, respectively. OCT showed low percentage of RAS (16 ± 9.6%), and low percentage of ISA (1.8 ± 2.4%). Mean EI was 0.86 ± 0.02 and SI 0.35 ± 0.14. OCT analysis showed one edge dissection and no scaffold fractures. Conclusions BVS deployment optimization using HPPD does not cause BVS disruption and is associated with a good BVS expansion, low rate of strut malapposition and edge dissections. © 2015 Wiley Periodicals, Inc.
URI: https://hdl.handle.net/11499/9642
https://doi.org/10.1002/ccd.26222
ISSN: 1522-1946
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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