Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/9721
Title: Ocular pulse amplitude and retina nerve fiber layer thickness in migraine patients without aura
Authors: Acer, Semra
Oğuzhanoğlu, Atilla
Çetin, Ebru Nevin
Ongun, Nedim
Pekel, Gökhan
Kaşıkçı,Alper
Yağcı, Ramazan
Keywords: Cerebrovascular disease
Choroidal perfusion
Nerve fiber
Ocular pulse amplitude
Retinal imaging
adult
blood pressure
comparative study
cross-sectional study
female
human
intraocular pressure
male
migraine with aura
nerve fiber
oculoplethysmography
optical coherence tomography
pathology
pathophysiology
perimetry
physiology
prospective study
retina ganglion cell
visual field
young adult
Adult
Blood Pressure
Cross-Sectional Studies
Female
Humans
Intraocular Pressure
Male
Migraine with Aura
Nerve Fibers
Prospective Studies
Retinal Ganglion Cells
Tomography, Optical Coherence
Tonometry, Ocular
Visual Field Tests
Visual Fields
Young Adult
Publisher: BioMed Central Ltd.
Abstract: Background: To evaluate the ocular pulse amplitude (OPA), the posterior pole asymmetry analysis (PPAA), the peripapillary retinal nerve fiber layer (RNFL) thickness, the ganglion cell layer (GCL) thickness, macular thickness and visual field testing in migraine patients without aura. Methods: In this prospective, cross-sectional and comparative study 38 migraine patients and 44 age and sex matched controls were included. OPA was measured by dynamic contour tonometry (DCT), PPAA, RNFL, GCL and macular thickness were measured by Heidelberg Spectral Domain Optical Coherence Tomography (SD-OCT) and standard perimetry was performed using the Humphrey automated field analyzer. Results: The difference in OPA was not statistically significant between the two groups (p?0.05). In the PPAA there was no significant difference between two hemispheres in each eye (p?0.05). The RNFL thickness was significantly reduced in the temporal and nasal superior sectors in the migraine group (p?0.05). The GCL and macular thickness measurements were thinner in migraine patients but the difference between groups was not statistically significant (p?0.05). There was no correlation between RNFL, GCL, macular thickness measurements and OPA values. There was no significant difference in the mean deviation (MD) and pattern standard deviation (PSD) between the two groups (p?0.05). Conclusions: Migraine patients without aura have normal OPA values, no significant asymmetry of the posterior pole and decreased peripapillary RNFL thickness in the temporal and nasal superior sectors compared with controls. These findings suggest that there is sectorial RNFL thinning in migraine patients without aura and pulsative choroidal blood flow may not be affected during the chronic course of disease. © 2016 Acer et al.
URI: https://hdl.handle.net/11499/9721
https://doi.org/10.1186/s12886-015-0180-2
ISSN: 1471-2415
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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