Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/9761
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dc.contributor.authorÖzay, Cennet-
dc.contributor.authorMammadov, Ramazan-
dc.date.accessioned2019-08-16T13:05:36Z
dc.date.available2019-08-16T13:05:36Z
dc.date.issued2016-
dc.identifier.issn0001-6837-
dc.identifier.urihttps://hdl.handle.net/11499/9761-
dc.description.abstractIn this research the phenolic composition, and antioxidant, antibacterial and cytotoxic activities of the methanolic extracts obtained from three Alyssum L. taxa (A. foliosum var. megalocarpum, A. simplex and A. strigosum subsp. strigosum) were investigated for the first time. The antioxidant activity of the extracts was evaluated by DPPH, metal chelating, phosphomolybdenum, ß-carotene/linoleic acid and ferric reducing power assays. In addition, total phenolic and flavonoid contents in the extracts were determined. The brine shrimp lethality test was used to screen for possible cytotoxic activity of the extracts. Also, the extracts were evaluated for cytotoxicity against three human cancer cell lines: MCF-7, H1299 and HeLa. HPLC analysis showed that cinnamic acid, chlorogenic acid and rutin were the major phenolics in extracts tested. Among the three Alyssum extracts evaluated, the highest biological activities were obtained from A. simplex compared to other two Alyssum L. taxa. Based upon its name, future studies will be targeted at investigating which components can be caused neurorehabilitation in Alyssum. © 2016, Polish Pharmaceutical Society. All rights reserved.en_US
dc.language.isoenen_US
dc.publisherPolish Pharmaceutical Societyen_US
dc.relation.ispartofActa Poloniae Pharmaceutica - Drug Researchen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlyssumen_US
dc.subjectBiological activityen_US
dc.subjectCytotoxicityen_US
dc.subjectMadworten_US
dc.subjectPhenolic compositionen_US
dc.subjectAlyssum foliosum var. megalocarpum extracten_US
dc.subjectAlyssum simplex extracten_US
dc.subjectAlyssum strigosum subsp. strigosum extracten_US
dc.subjectantibiotic agenten_US
dc.subjectantioxidanten_US
dc.subjectbutylcresolen_US
dc.subjectchlorogenic aciden_US
dc.subjectcinnamic aciden_US
dc.subjectcytotoxic agenten_US
dc.subjectferrous ionen_US
dc.subjectgentamicinen_US
dc.subjectoxacillinen_US
dc.subjectplant extracten_US
dc.subjectrutosideen_US
dc.subjectunclassified drugen_US
dc.subjectantineoplastic agenten_US
dc.subjectflavonoiden_US
dc.subjectAlyssum foliosum var. megalocarpumen_US
dc.subjectAlyssum simplexen_US
dc.subjectAlyssum strigosum subsp. strigosumen_US
dc.subjectantibacterial activityen_US
dc.subjectantioxidant activityen_US
dc.subjectantiproliferative activityen_US
dc.subjectArtemiaen_US
dc.subjectArticleen_US
dc.subjectBacillus subtilisen_US
dc.subjectbiological activityen_US
dc.subjectBrassicaceaeen_US
dc.subjectchemical compositionen_US
dc.subjectconcentration responseen_US
dc.subjectcontrolled studyen_US
dc.subjectcytotoxicityen_US
dc.subjectdrug cytotoxicityen_US
dc.subjectEC50en_US
dc.subjectEscherichia colien_US
dc.subjectHeLa cell lineen_US
dc.subjecthumanen_US
dc.subjecthuman cellen_US
dc.subjectIC50en_US
dc.subjectiron chelationen_US
dc.subjectLC50en_US
dc.subjectlung cancer cell lineen_US
dc.subjectMCF 7 cell lineen_US
dc.subjectMicrococcus luteusen_US
dc.subjectminimum inhibitory concentrationen_US
dc.subjectnonhumanen_US
dc.subjectPseudomonas aeruginosaen_US
dc.subjectSalmonella enterica serovar Enteritidisen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectanimalen_US
dc.subjectchemistryen_US
dc.subjecttumor cell lineen_US
dc.subjectAnimalsen_US
dc.subjectAntineoplastic Agents, Phytogenicen_US
dc.subjectAntioxidantsen_US
dc.subjectCell Line, Tumoren_US
dc.subjectFlavonoidsen_US
dc.subjectPlant Extractsen_US
dc.titleAssessment of some biological activities of Alyssum L. Known as madworten_US
dc.typeArticleen_US
dc.identifier.volume73en_US
dc.identifier.issue5en_US
dc.identifier.startpage1213
dc.identifier.startpage1213en_US
dc.identifier.endpage1220en_US
dc.authorid0000-0003-2218-5336-
dc.authorid0000-0002-1120-6122-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopus2-s2.0-84990934186en_US
dc.identifier.wosWOS:000394080700012en_US
dc.identifier.scopusqualityQ2-
dc.ownerPamukkale University-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.grantfulltextnone-
crisitem.author.dept17.02. Biology-
Appears in Collections:Fen-Edebiyat Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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