Role of diffusion weighted magnetic resonance imaging in a ratmodel of testicular torsion

Abstract

Objective: The purpose of this study was to investigate the usefulness of diffusion-weighted imaging (DWI) in the detection of different degrees of testicular torsion (TT) at the 8th hour and testicular salvageability at the 24th hour of torsion. Methods: 31 rats were randomly classified into 4 groups. In Group 1 (sham-control group), the left testicle was kept outside and replaced. Left testicles were kept outside and twisted 360 in Group 2, 720 in Group 3 and 1080 in Group 4. Later, DWI was performed at 8th and 24th hours. After DWI, bilateral radical orchiectomy and histopathological examination were performed. Apparent diffusion coefficient (ADC) maps were obtained with b-factors of 0 and 800smm22. Comparisons of ADC values and damage in testicles were performed with Kruskal-Wallis test. Results: Sensitivity of DWI in the diagnosis of TT was 12.5% for 360 torsion, 100% for 720 torsion and 1080 torsion at the 8th hour of torsion. Mean ADC values of the left testicles increased significantly at the 24th hour of torsion in Groups 3 and 4. All testicles in Groups 3 and 4 were observed to be irrecoverable on histopathological examination. Conclusion: Increased ADC values in the affected testicle may represent irreversible tissue damage. So, immediate surgery is not required at this stage, which may reduce morbidity and mortality caused by immediate surgery and anaesthesia. © 2016 The Authors.