Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/9870
Title: Neuroimaging evaluation of non-aneurismatic “top of the basilar” syndrome
Authors: Kıroğlu, Yılmaz.
Onur, Şule.
Herek, Duygu.
Ağladıoğlu, Kadir.
Teke, Eylem.
Çitişli, Veli.
Keywords: Anatomy
Atherosclerosis
Syndrome
Thromboembolus
Top of the basilar
adult
aged
artery dissection
artery occlusion
artery thrombosis
Article
atherosclerotic plaque
behavior disorder
brain atherosclerosis
brain dysfunction
brain region
brain stem infarction
cerebrovascular accident
clinical article
computed tomographic angiography
consciousness disorder
diffusion weighted imaging
digital subtraction angiography
female
functional neuroimaging
human
magnetic resonance angiography
male
motor dysfunction
nuclear magnetic resonance imaging
speech disorder
top of the basilar artery syndrome
vasculitis
visual disorder
Publisher: Ege University Press
Abstract: Purpose: We aim to evaluate the clinical and imaging features of “Top of the basilar” syndrome (TOB-S). Method: We retrospectively evaluated the clinical and imaging features of thirty consecutive TOB-S patients. We analyzed the ischemic parenchymal lesions and vascular disturbances with anatomic correlation by using magnetic resonance imaging (MRI), diffusion-weighted MRI (DWI), computed tomography angiography (CTA), magnetic resonance angiography (MRA), and digital subtraction angiography (DSA). Results: Thirty patients (14 males and 16 females) with a mean age of 61 years (range: 32–78 years) were diagnosed as TOB-S based on the neuroimaging and clinical findings. Large artery atherosclerosis (LAA) was the common etiology (63.3%), including the subgroups of in situ steno/occlusive, artery to artery embolus (AA), arterial branch (AB) occlusion, and AA+AB combination. The other etiologies were cardioembolism (CE) (16.6%), arterial dissection (AD) (10.0%), vasculitis (6.6%), and undetermined (3.3%). The patients represented ‘superficial', ‘deep' and ‘superficial plus deep' infarcts with segmental, territorial or scattered patterns. The most clinical manifestations were motor deficits, alteration of consciousness, visual/oculomotor disturbance, cerebellar dysfunction, behavioral disorder and speech disorder. Conclusion: The accurate evaluation of imaging findings in TOB-S is essential for diagnosis and appropriate management. Familiarity with the vascular anatomy, supplying territories, and infarction patterns of the ischemic lesions is crucial. © 2016, Ege University Press. All Rights Reserved.
URI: https://hdl.handle.net/11499/9870
ISSN: 1300-1817
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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