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https://hdl.handle.net/11499/9870
Title: | Neuroimaging evaluation of non-aneurismatic “top of the basilar” syndrome | Authors: | Kıroğlu, Yılmaz. Onur, Şule. Herek, Duygu. Ağladıoğlu, Kadir. Teke, Eylem. Çitişli, Veli. |
Keywords: | Anatomy Atherosclerosis Syndrome Thromboembolus Top of the basilar adult aged artery dissection artery occlusion artery thrombosis Article atherosclerotic plaque behavior disorder brain atherosclerosis brain dysfunction brain region brain stem infarction cerebrovascular accident clinical article computed tomographic angiography consciousness disorder diffusion weighted imaging digital subtraction angiography female functional neuroimaging human magnetic resonance angiography male motor dysfunction nuclear magnetic resonance imaging speech disorder top of the basilar artery syndrome vasculitis visual disorder |
Publisher: | Ege University Press | Abstract: | Purpose: We aim to evaluate the clinical and imaging features of “Top of the basilar” syndrome (TOB-S). Method: We retrospectively evaluated the clinical and imaging features of thirty consecutive TOB-S patients. We analyzed the ischemic parenchymal lesions and vascular disturbances with anatomic correlation by using magnetic resonance imaging (MRI), diffusion-weighted MRI (DWI), computed tomography angiography (CTA), magnetic resonance angiography (MRA), and digital subtraction angiography (DSA). Results: Thirty patients (14 males and 16 females) with a mean age of 61 years (range: 32–78 years) were diagnosed as TOB-S based on the neuroimaging and clinical findings. Large artery atherosclerosis (LAA) was the common etiology (63.3%), including the subgroups of in situ steno/occlusive, artery to artery embolus (AA), arterial branch (AB) occlusion, and AA+AB combination. The other etiologies were cardioembolism (CE) (16.6%), arterial dissection (AD) (10.0%), vasculitis (6.6%), and undetermined (3.3%). The patients represented ‘superficial', ‘deep' and ‘superficial plus deep' infarcts with segmental, territorial or scattered patterns. The most clinical manifestations were motor deficits, alteration of consciousness, visual/oculomotor disturbance, cerebellar dysfunction, behavioral disorder and speech disorder. Conclusion: The accurate evaluation of imaging findings in TOB-S is essential for diagnosis and appropriate management. Familiarity with the vascular anatomy, supplying territories, and infarction patterns of the ischemic lesions is crucial. © 2016, Ege University Press. All Rights Reserved. | URI: | https://hdl.handle.net/11499/9870 | ISSN: | 1300-1817 |
Appears in Collections: | Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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