Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/9903
Title: Value of high-sensitive cardiac troponin in predicting mortality in the emergency department
Authors: Kavasoglu, M.E.
Eken, C.
Eray, O.
Serinken, Mehmet Akif.
Gulen, B.
Keywords: Hashimoto's
Mean platelet volume
Neutrophil lymphocyte ratio
Thyroiditis
troponin
troponin T
acute coronary syndrome
adult
Article
cardiovascular mortality
cohort analysis
emergency ward
female
human
major clinical study
male
middle aged
outcome assessment
prognosis
protein blood level
reference value
sensitivity and specificity
validity
aged
area under the curve
blood
hospital emergency service
mortality
Acute Coronary Syndrome
Adult
Aged
Area Under Curve
Emergency Service, Hospital
Humans
Middle Aged
Reference Values
Troponin T
Publisher: Verlag Klinisches Labor GmbH
Abstract: Background: The present study aimed to determine the validity of hs-cTnT in predicting the mortality among patients presented to the emergency department (ED) likely to be acute coronary syndrome (ACS). Method: Patients in whom hs-cTnT was tested in the ED for a possible ACS composed the study cohort. Hs-cTnT levels of the study patients were obtained from the hospital computerized database. The outcome and mortality of the study patients was detected using the digitalized national mortality registry. All-cause mortality and cardiac mortality at the end of one month was the primary outcome. Results: 11795 patients were eligible for mortality detection and included into the final analysis. 1246 of 11795 patients were established to be dead during the study period and 358 of them supposed to be cardiac in origin. The Area Under the Curve (AUC) value of initial hs-cTnT for predicting one-month cardiac mortality was 0.869 (95% CI: 0.863-0.875) and 0.861 (95% CI: 0.855-0.867) for one-month all-cause mortality. The upper reference limit, 14 ng/L, has a sensitivity and specificity of 87% (95% CI: 77% to 94%) and 69% (95% CI: 68% to 70%), respectively, for predicting one-month cardiac mortality. Conclusions: The reference value of initial hs-cTnT does not have the ability to predict the cardiac mortality in a sufficient manner. However, reductions or increases in absolute or relative hs-cTnT levels are in concordance with mortality rates.
URI: https://hdl.handle.net/11499/9903
https://doi.org/10.7754/Clin.Lab.2016.151211
ISSN: 1433-6510
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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