Liquid phase determination of adrenaline uses a voltammetric sensor employing CuFe2O4 nanoparticles and room temperature ionic liquids

Abstract

A highly sensitive and quick voltammetric sensor based on CuFe2O4 nanoparticle/room temperature ionic liquids carbon paste electrode (CuFe2O4/ILs/CPE) is proposed for the determination of adrenaline in the biological condition (pH = 7.4). CuFe2O4 are nanoparticles synthesized by co-precipitation method and characterized with different methods such as transmission electron microscopy (TEM) and X-ray diffraction (XRD). In continuous, we study application of the CuFe2O4 nanoparticle for the preparation of carbon paste electrode modified with 1,3-dipropylimidazolium bromide as a suitable and high conductive binder. At the best condition (pH 7.4), the peak currents of square wave voltammograms (SWV) of adrenaline increased linearly with its concentration in the ranges of 0.1-400 µM. The detection limit for adrenaline was 0.07 µM. The modified sensor has been successfully applied for the assay of adrenaline in biological and pharmaceutical samples such as urine and injection in comparison with other method. © 2015 Elsevier B.V. All rights reserved.