Acıpayam Meslek Yüksekokulu Koleksiyonu
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Article Effect of Carob Aqueous Extract on Boron, Copper, Zinc, Iron, and Vitamin C Levels in Brain, Heart, Liver, and Kidney Tissues of Diabetic Wistar Albino Rats(Wiley, 2026-03-29) Basegmez, Mehmet; Eryavuz, Azra Mila; Avsar, Mehmet Talha; Atik, Hulya Demirkapi; Demirel, Hasan Huseyin; Durmus, Ibrahim; Eryavuz, AbdullahThe utilization of medicinal plants in diabetes mellitus treatment is increasing owing to their effectiveness and safety compared to synthetic drugs. Thus, this study aimed to evaluate the effects of the aqueous extract of carob on tissue trace element levels, vitamin C concentrations, and histopathological alterations in streptozotocin-nicotinamide (STZ-NA)-induced diabetic Wistar albino rats. Rats were randomly divided into four experimental groups: control, diabetes, carob, and diabetes + carob. Following diabetes induction, rats in the diabetes + carob group were treated with carob aqueous extract during the experimental period. At the end of the study, tissue samples from the brain, liver, heart, and kidney were collected from rats. The samples were analyzed to determine vitamin C levels as well as trace elements, including boron (B), copper (Cu), zinc (Zn), and iron (Fe). Additionally, histopathological changes in collected tissues were examined. Diabetes significantly reduced vitamin C levels in brain and kidney tissues (p < 0.05), whereas no significant change was observed in the heart and liver (p > 0.05). Carob extract administration significantly increased tissue vitamin C levels in both diabetic and non-diabetic rats (p < 0.05). Additionally, both diabetes and carob aqueous extract administration were found to alter tissue trace mineral composition. In conclusion, the study demonstrates that carob aqueous extract can have an effect on tissue vitamin C and some trace mineral levels in normal and diabetic rats.Article Digital Transformation and the Evolution of Professional Identity: A Qualitative Study on the Perceptions of Office Management and Secretarial Students(Wiley, 2026-01) Ergun; Husnu; Ergün, HüsnüTo date, understanding the future of the office management and secretarial profession, which is rapidly changing under the influence of technology, has consistently been approached through sector-based analyses. This study, however, shifts the perspective to focus on the hearts and minds of the young people preparing for this journey. Using a qualitative approach, the research is aimed at identifying the perceptions of participants by investigating whether they view this digital transformation as a threat or an opportunity and how it affects their career aspirations and professional identities. The participants are students at the department of office management and secretarial studies within a vocational school of a state university. Interviews with a total of 22 participants were analyzed under the themes of productivity and business processes, job security and professional transformation, remote work experience, cybersecurity concerns, and socioethical impacts. The findings indicate that while digital tools (e.g., ERP, cloud systems) increase operational efficiency, digital adaptation requires time. Artificial intelligence and automation are leading to the evolution of traditional roles into titles such as digital assistant coordinator, making proficiency in digital work management tools a necessity. Although remote work initially posed social and technical challenges, productivity was maintained through digital discipline. While cyber risks like data breaches necessitate proactive measures, ethical and social issues have been highlighted, such as the impact of human-machine interaction, the erosion of social bonds, and clients ' need for human contact. The research underscores that digitalization is intertwined with technological, pedagogical, and social dynamics. It is recommended that educational programs be updated to include data analytics, ethical sensitivity, and strategic skills. By examining professional transformation from the student perspective, this study fills a gap in the literature; for future research, the inclusion of quantitative methods and the involvement of industry stakeholders is recommended.Article Citation - WoS: 1Citation - Scopus: 3Probiotic viability and bioactive properties of buffalo yoghurt produced using high cholesterol-assimilating probiotic strains(Wiley, 2025-02-06) Akbal, Sinan; Gecer, Esra Ugur; Ertuerkmen, PelinBackgroundThis study aimed to produce yoghurt with reduced cholesterol levels, enhanced antioxidant activity and angiotensin-converting enzyme (ACE) inhibitory activity while maintaining acceptable health properties, using buffalo milk and probiotic microorganisms.MethodBuffalo yoghurts were produced using three different probiotic strains, including Lactobacillus acidophilus, Lactiplantibacillus plantarum and Bifidobacterium lactis. ACE-inhibitor activities (%), antioxidant activities as DPPH (%), and cholesterol activities in HPLC of these yoghurts were determined during the 28-day storage period. In addition, probiotic microorganisms, total aerobic mesophilic bacteria and yeast mould were counted during storage.ResultsThe viability of probiotic microorganisms in buffalo yoghurts remained above 5 log CFU/g at the end of the storage period. Antioxidant activity ranged from 9.30% to 27.20%. Buffalo yoghurt is produced with Lpb. plantarum, which exhibited the highest viability (9.12 log CFU/g) and antioxidant activity values of 61.48%. Gastrointestinal digestion affected the antioxidant and ACE-inhibitor properties of the yoghurt samples. The highest ACE-inhibitory effect after gastric digestion on the 28th day was observed in yoghurt-produced Lpb. plantarum and B. lactis, with 24.30% and 25.14% values, respectively. Also, the ACE-inhibitory activity of the outer (OUT) phase for all yoghurt samples was higher than that of undigested samples. According to cholesterol peaks obtained in HPLC, the highest cholesterol assimilation was detected in yoghurt produced using Lpb. plantarum.ConclusionThe data obtained from the study may contribute to research on the potential of probiotic microorganisms with cholesterol-assimilation ability and probiotic food products produced using them to reduce cholesterol risk.Conference Object Comparison of Heavy Metal, Total Oxidant and Antioxidant Levels in Umbilical Cord Blood of Women Living in Rural and Urban Areas(Wiley, 2024) Basegmez, M.; Yigit, A. A.; Simsek, O.[No Abstract Available]