Diş Hekimliği Fakültesi Koleksiyonu
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Article Citation - WoS: 4Citation - Scopus: 5Gastric Acid Challenge: Mechanical Proficiency and Surface Gloss of Tooth-Colored Restorative Materials(Bmc, 2025-04-21) Yenidunya, Ozge Gizem; Misilli, Tugba; Yilmaz, EbruBackgroundTo evaluate surface microhardness, roughness, and gloss changes of tooth-colored restorative materials [a direct composite (G-aenial A'Chord), an indirect composite (Gradia Plus), an ormocer (Admira Fusion), a giomer (Beautifil II), and an alkasite (Cention N)] after exposure to simulated gastric acid.MethodsA total of 110 disc-shaped specimens (22 discs of each material) were prepared using silicone molds (8 mmx2 mm) and exposed to either gastric acid or artificial saliva (control). Surface roughness (Ra), gloss (GU), and microhardness (VHN) were measured at baseline and after 96-hour of immersion in the solutions and the respective changes (triangle Ra, triangle GU, triangle VHN) were calculated. Intergroup comparisons were performed using ANOVA (Tukey post hoc) or Kruskal-Wallis tests (Bonferroni correction). Independent samples t-test or Mann-Whitney U test was used for comparisons of each material across immersion media, while paired t-test was applied for time-dependent analyses.ResultsIn the gastric acid medium, changes in all parameters led to significant differences among restorative materials, while in the artificial saliva medium, significant differences were observed in triangle VHN and triangle GU. The statistically significant difference between immersion media was observed in both triangle VHN and triangle Ra values for the giomer group, and in only triangle VHN values for the alkasite and indirect composite groups. In the gastric acid medium, the decrease in VHN and GU values was significant across all subgroups, while the increase in Ra was statistically significant only in the giomer and alkasite groups.ConclusionsWhile the giomer group exhibited the most significant changes in roughness and microhardness following exposure to gastric acid, all tested materials executed clinically admissible results regarding surface gloss.Clinical trial numberNot applicable.Article Citation - WoS: 4Citation - Scopus: 4Effects of Orientation and Postprocessing on the Bonding of 3-Dimensional Printed Brackets To Printable Permanent Crown Resin(Mosby-Elsevier, 2025-03) Cokakoglu, Serpil; Karaokutan, Isil; Buyuk, Suleyman KutalmisIntroduction: This study aimed to evaluate the effects of different printing orientations and postcuring processes on the bonding performance of 3-dimensional (3D)-printed brackets to permanent crown resin. Methods: A total of 90 disk-shaped specimens (2 mm thickness and 10 mm diameter) were manufactured from printable resin material (Formlabs Permanent Crown, Formlabs Inc, Somerville, Mass). The 3D printed brackets were fabricated at 3 build angles (0 degrees, 45 degrees, and 90 degrees) with a 50 mm layer thickness. Each group consisted of 30 brackets. After printing, the postprocessing was performed either with or without glycerin immersion. Each printed resin surface and bracket base were sandblasted with 50 mm aluminum oxide particles before the bonding procedure. The 3D printed brackets were bonded with a conventional orthodontic composite resin (Transbond XT Primer, 3M Unitek, Monrovia, Calif) to printable resin surfaces. After thermal cycling, the shear bond strength (SBS) test was applied, and bonding failure was examined under a stereomicroscope at 103 magnification. Two-way analysis of variance, post-hoc Tukey, and chi-square tests were used for data analysis. Results: Both orientation and postprocessing had significant effects on SBS. The 3D-printed brackets with 90 degrees and glycerin immersion postcuring demonstrated the highest (13.74 +/- 4.52 MPa), whereas 45 degrees orientation without glycerin showed the lowest (7.06 +/- 4.32 MPa) SBS. All specimens had cohesive-type bonding failures mainly accompanied by bracket fractures and without surface damage. The least fracture was found in 3D-printed brackets with the highest SBS. Conclusions: The 3D printed brackets with 90 degrees orientation and glycerin immersion postprocessing demonstrated the best bonding performance when applied to the printable permanent crown resin material. (Am J Orthod Dentofacial Orthop 2025;167:362-70)Article Citation - WoS: 2Citation - Scopus: 3Automated Age Estimation From Opg Images and Patient Records Using Deep Feature Extraction and Modified Genetic-Random Forest(Mdpi, 2025-01-29) Ozlu Ucan, Gulfem; Gwassi, Omar Abboosh Hussein; Apaydin, Burak Kerem; Ucan, BahadirBackground/Objectives: Dental age estimation is a vital component of forensic science, helping to determine the identity and actual age of an individual. However, its effectiveness is challenged by methodological variability and biological differences between individuals. Therefore, to overcome the drawbacks such as the dependence on manual measurements, requiring a lot of time and effort, and the difficulty of routine clinical application due to large sample sizes, we aimed to automatically estimate tooth age from panoramic radiographs (OPGs) using artificial intelligence (AI) algorithms. Methods: Two-Dimensional Deep Convolutional Neural Network (2D-DCNN) and One-Dimensional Deep Convolutional Neural Network (1D-DCNN) techniques were used to extract features from panoramic radiographs and patient records. To perform age estimation using feature information, Genetic algorithm (GA) and Random Forest algorithm (RF) were modified, combined, and defined as Modified Genetic-Random Forest Algorithm (MG-RF). The performance of the system used in our study was analyzed based on the MSE, MAE, RMSE, and R2 values calculated during the implementation of the code. Results: As a result of the applied algorithms, the MSE value was 0.00027, MAE value was 0.0079, RMSE was 0.0888, and R2 score was 0.999. Conclusions: The findings of our study indicate that the AI-based system employed herein is an effective tool for age detection. Consequently, we propose that this technology could be utilized in forensic sciences in the future.Article Citation - WoS: 1Citation - Scopus: 1Turkish Dentist Practice and Opinions on Diagnosing and Treating Deep Caries Lesions: a Web-Based Survey(BioMed Central Ltd, 2025-02-08) Akgul, Nilgun; Yilmaz, Ebru; Akkurt, Onur; Yenidunya, Ozge GizemBackground: This study investigated the practices and opinions of Turkish dentists regarding the management of deep caries lesions using an online questionnaire. Methods: The questionnaire had two sections: the first collected demographic data, while the second focused on clinical practices, including radiographic techniques, rubber dam usage, liner choices, pulp protection, and post-endodontic restoration methods. Results: The survey response rate was 20.4%. 18 participants were excluded due to incomplete responses in the survey. A total of 390 survey texts (19.5%) were analyzed. The gender distribution of the participants was as follows: 60% female and 40% male. Notably, none of the respondents used rubber dams for endodontic treatment. Male dentists were less likely to use a base under restorations (p < 0.05). Female dentists preferred single-session pulp capping for pulpal perforations (p < 0.05). Public hospitals utilized fewer panoramic films, while Oral and Dental Health Centers used fewer periapical films for diagnoses (p < 0.05). Glass ionomer cement was the most commonly used base material, and direct composite resin was the preferred choice for post-endodontic restorations, in contrast to the less favored indirect composite resin. Conclusions: Despite its advantages, the application of rubber dam was infrequent. Glass ionomer cement emerged as the predominant base material across all restoration types, exhibiting variability among dentists in diagnosis, treatment, and material selection. © The Author(s) 2025.Article Citation - WoS: 8Citation - Scopus: 9Efficacy of injectable platelet-rich fibrin on clinical and biochemical parameters in non-surgical periodontal treatment: a split-mouth randomized controlled trial(Springer Science and Business Media Deutschland GmbH, 2023-12-28) Cin, Gizem Torumtay; Alpan, Aysan Lektemur; Cevik, OezgeAbstract: Objectives: The purpose of this clinical trial was to evaluate the potential clinical and biochemical effects of injectable platelet-rich fibrin (i-PRF) application adjunct to scaling and root planning (ScRp) in deep periodontal pockets. Materials and methods: In this split-mouth-designed study, 17 patients with 34 deep periodontal pockets were randomly treated with ScRp + i-PRF (test group) and ScRp + saline (control group). Clinical periodontal measurements were recorded at baseline, 1st, 3rd, and 6th months after the treatments. The levels of vascular endothelial growth factor (VEGF), tumor necrosis factor-α (TNF-α), and interleukin (IL)-10 in gingival crevicular fluid (GCF) samples were analyzed using the ELISA method at baseline, 7th, and 14th days. Results: Clinical periodontal parameters showed significant improvements with both treatment modalities. Mean pocket reduction (PD) and clinical attachment (CAL) gain were significantly higher in the test group than in controls at follow-up visits (p < 0.05). In the test group, gingival recession (GR) values were significantly lower compared to the control group. VEGF and IL-10 levels in the test group were significantly higher than in controls at the 14th day, and TNF-α levels were found significantly lower in the test group at the 7th and 14th days. Conclusions: Especially in the test group, the significant increase in VEGF and IL-10 expressions and the decrease in TNF-α levels may have accelerated the periodontal healing observed in the clinical parameters. Clinical relevance: The result of the present study demonstrated the beneficial effects of adjunctive i-PRF administration during non-surgical periodontal treatment of deep periodontal pockets. Clinical trial registration number: NCT05753631. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.Article Citation - WoS: 6Citation - Scopus: 5The effects of severe periodontitis on arterial stiffness using cardio-ankle vascular index in patients with type 2 diabetes(Wiley, 2023-11) Cin, Gizem Torumtay; Fenkci, Semin Melahat; Kilic, Ismail Dogu; Aslan, Halil Serdar; Sevgican, Cihan Ilyas; Senol, HandeBackground and Objective: Arterial stiffness, which is a measure of the elasticity of the arteries, is also a risk factor for the development of cardiovascular diseases and its measurement is important for evaluating the atherosclerosis process. The purpose of this cross-sectional study to investigate whether severe periodontitis in short-term type 2 diabetes may be associated with increased cardio-ankle vascular index (CAVI) values specified for subclinical atherosclerosis risk.Methods: A total of 136 subjects, including 69 subjects with short-term type 2 diabetes (35 with severe periodontitis and 34 with periodontally healthy) and 67 systemically healthy subjects (32 with severe periodontitis and 35 with periodontally healthy) were enrolled to this study. Assessment of all participants included in this study in terms of arterial stiffness was determined by CAVI. Serum fasting plasma glucose (FPG), glycated haemoglobin (HbA1c), triglyceride (TRG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol (TC) and C-reactive protein (CRP) levels were calculated using standard methods. Full mouth periodontal measurements were recorded. Multiple linear regression analysis was performed to evaluate the relationship between periodontal parameters and mean CAVI values of the groups.Results: Mean CAVI levels were significantly higher in diabetic and periodontitis group compared to the other study groups (p < .05). In diabetes and periodontitis group, CAVI was showed positive correlations with CRP (r = .337, p = .048) and HbA1c (r = .442, p = .008). Also, positive significant correlations were found with probing depth (PD) and clinical attachment level (CAL) in the periodontitis groups. Multiple regression analysis revealed that CAL independently predicted CAVI levels in periodontitis groups (beta = .433, p = .019 in diabetes and periodontitis groups and beta = .57, p = .001 in systemically healthy and periodontitis group respectively).Conclusion: This is the first study investigating the association between severe periodontitis and CAVI in patients with short-term diabetes. Our findings suggest that severe periodontitis may be an intermediate factor in the pathway between type 2 diabetes and cardiovascular disease by increasing the arterial stiffness.Article Citation - WoS: 3Citation - Scopus: 6Effects of different universal adhesives and surface treatments on repair bond strength between resin composites(John Wiley and Sons Inc, 2022-05-16) Yilmaz, Fatma; Yazkan, Basak; Herguner Siso, SeydaObjective: This study aimed to evaluate the effects of different universal adhesives and surface treatments on the repair bond strength between resin composites. Materials and Methods: A total of 220 composite samples were divided into three groups according to the adhesive resin to be applied: 1) Scotchbond Universal, 2) G-Premio Bond, and 3) Peak Universal Bond. They were then divided into seven subgroups according to surface treatments (n = 10): A) air abrasion, B) air abrasion+silane, C) hydrofluoric acid, D) hydrofluoric acid+silane, E) air abrasion+hydrofluoric acid+silane, F) silane, and G) no surface treatment (negative control). After surface treatment, a repair composite was applied. Samples aged in the thermocycle were subjected to micro-tensile bond strength testing. Cohesive strength values of 10 non-aged composite blocks were used as a positive control. Kruskal–Wallis and one-way ANOVA tests were used for statistical evaluation. Fractured surfaces were evaluated using a scanning electron microscope. Results: In Scotchbond Universal and G-Premio Bond, the mean micro-tensile bond strength value of the no surface treatment subgroup was significantly lower than that of the positive control. All subgroups of Peak Universal Bond showed similar values to the positive control. Conclusion: While Scotchbond Universal and G-Premio Bond required mechanical roughening before adhesive application, Peak Universal Bond did not require any surface treatment. Clinical Significance: Different universal adhesives may show different repair bonding strengths with different surface treatments. Since achieving a standard in this regard can be associated with many independent factors, clinicians should determine how to apply the adhesive they use most effectively with the most appropriate surface treatment based on their own clinical experience. © 2022 Wiley Periodicals LLC.Article Citation - WoS: 3Citation - Scopus: 4Early extraction of the first permanent molars: a five-year follow-up study(Ariesdue Srl, 2022) Ertugrul, C. C.; Ozbey, H.; Gun, A. I.Aim Early extraction of first permanent molars (FPMs) is generally considered successful when the second permanent molar and premolar come into contact, regardless of whether the patient has a healthy occlusion. In this study, we aimed to investigate cases in which early extraction had a successful prognosis. Methods Study design: Pre-extraction orthopantomograms of children whose one or more FPMs were extracted were examined retrospectively. Post-extraction parameters such as status of the extraction gap, any other diastema formation, and midline shift were evaluated clinically and radiographically. For the dental age estimations, development levels of the teeth were scored using the Demirjian method and the developmental status of a particular tooth was calculated in years based on tables given by Willems et al. [2001]. The ICON index was used to determine the orthodontic treatment needs of patients. Statistics: Descriptive analyses and the Kruskal-Wallis test were used for the statistical analysis of the data. Results Twenty-six patients with 40 extracted FPM were followed-up for an average of 61.12 months. The mean chronological and dental ages of the patients at the time of extraction were 9.98 +/- 1.35 and 10.65 +/- 1.39 years, respectively. Closure of the extraction gap occurred in 83.3% and 78.5% of the cases in the maxilla and mandible, respectively. However, when the cases with the formation of a diastema between the other teeth and/or midline shift were assumed to have failed, success rates decreased to 50% in the maxilla and 17.8% in the mandible. Conclusions Early extraction of FPM should be considered successful when there is no formation of any other diastema in the relevant quadrant, midline shift, or orthodontic treatment needs due to extraction.Article Citation - WoS: 9Citation - Scopus: 8The effect of different cleaning agents and resin cement materials on the bond strength of contaminated zirconia(Wiley, 2021-10-06) Sahin, Sezgi Cinel; Celik, ErsanThe purpose of this study was to examine the effect of different cleaning methods and resin cements on the shear bond strength (SBS) of contaminated zirconia. A total of 92 disc-shaped zirconia specimens were contaminated with different procedures. Then, the specimens were grouped according to cleaning methods and resin cements: no cleaning + Variolink Esthetic DC (CNV), no cleaning + Panavia V5 (CNP), sandblasted + Variolink Esthetic DC (SBV), sandblasted + Panavia V5 (SBP), Ivoclean + Variolink Esthetic DC (ICV), Ivoclean + Panavia V5 (ICP), Katana Cleaner + Variolink Esthetic DC (KCV), and Katana Cleaner + Panavia V5 (KCP). Following an aging protocol in a 37 degrees C for 1 week, SBS analysis was performed with a universal test machine. For the surface topography and elemental analysis, scanning electron microscopy and energy-dispersive X-ray spectroscopy (EDS) were used. Significance was evaluated as p < .05 and p < .01. The highest SBS results were found in the SBP group, showing a statistically significant difference from all other groups (p < .05). For the same cleaning method, Panavia V5 showed statistically significantly higher SBS values than Variolink Esthetic DC (p < .01), except the CNP-CNV (p = .880) and KCP-KCV (p = .082) groups. The most detected surface elements by EDS were Zr, O, C, and N, respectively. The contaminated zirconia surfaces must be cleaned for successful adhesion. The use of phosphate-containing adhesives in combination with sandblasting will increase the adhesion strength, and universal cleaning agents can be a good alternative to sandblasting.Article Citation - WoS: 7Citation - Scopus: 9The effect of pre-operative submucosal administration of dexamethasone, tramadol, articaine on the success rate of inferior alveolar nerve block on mandibular molars with symptomatic irreversible pulpitis: A randomized, double-blind placebo-controlled clinical trial(Wiley, 2021-08-25) Aksoy, Fatih; Ege, Bilal; Tosun, SametAim To establish the effects of submucosal tramadol, dexamethasone and articaine on the success of inferior alveolar nerve blocks (IANB) during root canal treatment of mandibular molars with symptomatic irreversible pulpitis (SIP). Methodology In this randomized double-blind, controlled clinical trial, 120 patients with the diagnosis of SIP in their mandibular first or second molars were included and randomly divided into four groups (n = 30). The control group received normal saline and three experimental groups received a single dose of dexamethasone (8 mg/2 mL), or tramadol (100 mg/2 mL) or articaine (4% / 2 mL). The pre-operative pain levels of the patients were measured with the Heft-Parker visual analogue scale (HP VAS). All patients received standard IANB of 4% articaine with 1:200000 epinephrine. Following the observation of lip numbness, submucosal injections were administered into the mucobuccal fold adjacent to the mandibular molars. After 15 min, standard root canal treatment was initiated, and the pain intensity levels recorded from the access cavity preparation to pulp extirpation were measured with HP VAS. The duration of the anaesthesia was also evaluated. The experimental groups were compared using one-way ANOVA or Kruskal-Wallis H-test. The groups that were significantly different were compared pairwise using the Tukey Multiple Comparison test. The Chi-square test was used to compare the categorical variables. Results The submucosal administration of articaine significantly increased the success rate to 63% in comparison with the control group that received submucosal saline (p < .05). The success rate of pulpal anaesthesia was 37% in the control group, 57% in the tramadol group and 47% in the dexamethasone group, with no significant difference in the success rate among these groups. In the dexamethasone group, the duration of the anaesthetic effect of IANB was significantly longer than those in the other groups (p < .001). Conclusions In patients with SIP, pre-operative submucosal administration of articaine increased the success rate of IANB, while administration of dexamethasone increased the duration of anaesthesia. These agents can be used in cases where effective anaesthesia cannot be obtained during root canal treatments.