Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/23212
Title: The influence of iris color and retina pigment epithelium melanin on allergic rhinitis
Other Titles: İris rengi ve retina pigment epitel melanininin alerjik rinite olan etkisi
Authors: Derekoy, S
Kenar, Fethullah
Yavas, GF
Kusbeci, T
Öztürk, Faruk
Aycicek, A
Keywords: Allergic rhinitis; iris color; retina pigment epithelium; Arden ratio;
melanin
Publisher: DEOMED PUBL, ISTANBUL
Abstract: Objective: The purpose of this case control study is to establish the influence of iris color and retina pigment epithelium melanin on allergic rhinitis.
Methods: Ninety-nine subjects diagnosed prospectively as allergic rhinitis and 85 control subjects were included in the study. Color of iris was recorded after ophthalmic examination. Electro-oculographic measurement was done after pupil dilatation and Arden ratios were recorded.
Results: Mean age was 29.44 +/- 9.8 years in subject with allergic rhinitis and 32.67 +/- 12.9 years in control subjects (p>0.05). Measured mean Arden ratio was 158.22 +/- 29.4 in subjects with allergic rhinitis and 179.34 +/- 29.3 in normal subjects (p<0.05). In control group, Arden ratio was significantly higher in eyes with brown iris (p<0.05). In subjects with allergic rhinitis, Arden ratio was significantly lower in brown eyes (p<0.05).
Conclusion: An association between allergic rhinitis and melanin content of iris and retina pigment epithelium was found. It can be speculated that pigment-producing system may play a role in the pathogenesis of the allergic rhinitis.
URI: https://hdl.handle.net/11499/23212
https://doi.org/10.2399/jmu.2016001006
ISSN: 2149-7109
Appears in Collections:Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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