KRONİK OBSTRÜKTİF AKCİĞER HASTALARINDA FARKLI GOLD EVRELERİNE GÖRE YAŞAM KALİTESİ VE BODE İNDEKSİ

Abstract

QUALITY OF LIFE AND BODE INDEX ACCORDING TO DIFFERENT GOLD STAGES IN COPD PATIENTS INTR0DUCTION: Chronic obstructive pulmonary disase (COPD) is in the 4th order in the chronic and frequent morbidity and mortality etiologies. Severity of COPD was made only according to FEV1 (%RESPECTED) in old GOLD staging. But new GOLD staging was developed with symptom stage, frequency of exacerbations and comorbidities as old GOLD staging was thought as inadequate for dyspnea severity, prognosis and quality of life. We analysed the differences in SGRQ quality of life and BODE index between old and new GOLD staging in that study. MATERIAL AND METHOD: 91 patients were taken into the study follwed in Pamukkale University Medical Faculty COPD clinic. Body mass indices were calculated as kg/m2 via quantifying weight and height of all patients taken into the study.Spiromertical measurements were made according to ERS and ATS criteria. Six minute walking test was applied. Among quality tests; mMRC, OTD, BDI, BORG and SGRQ quality test were applied. Acute attack frequency and duration in last year were questioned in SGRQ scala. RESULTS: When we classified 91 COPD patients taken into the study, according to the old an new GOLD staging, 9 of 11 patients of stage 1 grouped as GOLD stage A, while 2 grouped as stage B. 26 of 50 patients of stage 2 grouped as GOLD stage A, 9 grouped as B, 6 grouped as C and 9grouped as stage D. 8 of 19 patients of stage 3 grouped as C, 11 grouped as D . 1 of 11 patients of stage 4 grouped as C and 10 grouped as D. Statistically significant decreases were seen in FEV1 ( %RESPECTED) (p= 0,001), SaO2% (p=0,001) and 6 MWD (p=0,001) as stage was progressing an both GOLD staging system in our study. Statistically significant deterioration was seen in all dyspnea scala (mMRC, BORG, OTD and BDI) (work, activity, capacity) and quality of life scoring SGRQ symptom, SGRQ activity, SGRQ respond and SGRQ total] as the stage progresses in both GOLD staging system (p=0,001). There was no significant difference in attack frequency in both GOLD staging (p=0,4; p=0,1 respectively) but there was significant difference in attack duration (p=0,03) in both COPD staging. CONCLUSION: This study shows that dyspnea severity, quality of life, prognosis were all becoming worse as stage progresses in both old and new GOLD staging. Furthermore, more worsening of group B patients than group C patients shows that symptoms are more important.