Synthesis and characterization of new partially-aggregated water-soluble polyether-triazole linked zinc(II) phthalocyanines as photosensitizers for PDT studies

Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/37253

Title:	Synthesis and characterization of new partially-aggregated water-soluble polyether-triazole linked zinc(II) phthalocyanines as photosensitizers for PDT studies
Authors:	Bayğu, Yasemin Gök, Y.
Keywords:	Click reaction Ester hydrolysis Partially-aggregation PDT Red shift Zinc phthalocyanine Gas generators Photodynamic therapy Photosensitizers Red Shift Multistep reactions Phthalonitriles Singlet oxygen generation Spectral data Synthesis and characterizations Zinc phthalocyanines Zinc compounds
Publisher:	Elsevier Ltd
Abstract:	Peripheral and non-peripheral octa-carboxylated water-soluble zinc(II) phthalocyanines with clicked polyethylene glycol linkers have been prepared. Different multistep reaction pathways have been attempted and compared for the preparation of the phthalonitrile precursors. Novel compounds have been characterized by combination of elemental analysis, 1H and 13C NMR, FT-IR, U–vis and MS spectral data. Both phthalocyanines were proved to be water soluble. Their singlet oxygen generation was determined in both water and DMSO to assess their potential of photosensitizers for photodynamic therapy. © 2019 Elsevier B.V.
URI:	https://hdl.handle.net/11499/37253 https://doi.org/10.1016/j.synthmet.2019.116256
ISSN:	0379-6779
Appears in Collections:	Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tavas Meslek Yüksekokulu Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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