Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/47881
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dc.contributor.authorİyilikçi, Berrin-
dc.contributor.authorTaşdemir, Ufuk-
dc.contributor.authorÖzmen, Özlem-
dc.contributor.authorKızıldağ, Alper-
dc.date.accessioned2023-01-09T21:30:34Z-
dc.date.available2023-01-09T21:30:34Z-
dc.date.issued2021-
dc.identifier.issn2146-2852-
dc.identifier.urihttps://doi.org/10.7126/cumudj.943229-
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1109817-
dc.identifier.urihttps://hdl.handle.net/11499/47881-
dc.description.abstractObjectives: The goal of this study was to observe the regenerative potential of Tideglusib in combination with autogenous and xenograft mandibular defects in rats. Material Methods: Our study consists of five groups: one control and four experimental. In 40 Wistar albino rats, 5-mm-diameter critical bone defects were created at the angle of the mandible. In the control group, the defect was not filled. The defects were grafted only Xenograft in Group 1, with Xenograft and tideglusib in Group 2, and with only autogenous bone graft in Group3, and with autogenous bone graft mixed with tideglusib in Group 4. Results: Sterological analyses revealed that enhanced new bone formation in the Group 4 compare to Control and Group 1. Immunohistochemically marked expressions of BMP-2 and VEGF were observed in Group 4. Conclusions: Our results demonstrated that Tideglusib, in combination with bone grafting has an adjuvant effect on BMP-2 and VEGF-A expressions that may accelerate bone regeneration © 2021,Cumhuriyet Dental Journal.All Rights Reserveden_US
dc.description.sponsorship2018DİŞF011en_US
dc.description.sponsorshipThis study was supported by the Scientific Research Project Fund of Pamukkale University. (Project Number: 2018DİŞF011)en_US
dc.language.isoenen_US
dc.publisherCumhuriyet University Faculty of Dentistryen_US
dc.relation.ispartofCumhuriyet Dental Journalen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAutogenous Bone Graften_US
dc.subjectBMP-2en_US
dc.subjectBone healingen_US
dc.subjectTideglusiben_US
dc.subjectVEGF-Aen_US
dc.titleEffect Of Tideglusib With Bone Grafting On New Bone Formationen_US
dc.typeArticleen_US
dc.identifier.volume24en_US
dc.identifier.issue3en_US
dc.identifier.startpage224en_US
dc.identifier.endpage231en_US
dc.identifier.doi10.7126/cumudj.943229-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid57210807926-
dc.authorscopusid56499067400-
dc.authorscopusid6602100853-
dc.authorscopusid55554424000-
dc.identifier.scopus2-s2.0-85116019940en_US
dc.identifier.trdizinid1109817en_US
dc.identifier.scopusqualityQ4-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
item.cerifentitytypePublications-
item.languageiso639-1en-
crisitem.author.dept06.01. Clinical Sciences-
crisitem.author.dept06.01. Clinical Sciences-
Appears in Collections:Diş Hekimliği Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
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