Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/50462
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dc.contributor.authorTokgun, Pervin Elvan-
dc.contributor.authorTomatir, Ayse Gaye-
dc.date.accessioned2023-04-08T10:00:05Z-
dc.date.available2023-04-08T10:00:05Z-
dc.date.issued2023-
dc.identifier.issn1305-6441-
dc.identifier.urihttps://doi.org/10.26650/IUITFD.1200910-
dc.descriptionTokgun, Pervin Elvan/0000-0001-9025-4140en_US
dc.description.abstractObjective: Breast cancer is associated with a 5% genetic predisposition in women. Mitochondria play a role in important cellular events such as metabolism, cell death, and inflammation. Recent studies have highlighted precursor micro-RNA (pre-miRNA) to be located in mitochondria as well as mature miRNA. This study aims to reveal the occurrence of mitochondrial miRNA (mitomiR) in breast cancer cells. Materials and Methods: The study has prepared the mitochondrial fractions using the magnetic-activated cell sorting (MACS) method and performed small RNA (sRNA) sequencing. Results: The study has identified known and novel mitomiR sequences aligned to the mitochondrial genome. Conclusion: Identifying new mitomiRs can provide significant contributions and illuminate the molecular mechanism underlying mitomiR biogenesis.en_US
dc.description.sponsorshipPamukkale University Scientific Research Projects Department [2014SBE011]en_US
dc.description.sponsorshipThis study is supported by Pamukkale University Scientific Research Projects Department (Project No: 2014SBE011).en_US
dc.language.isoenen_US
dc.publisherIstanbul Univ, Fac Medicine, Publ offen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMitomirsen_US
dc.subjectMacsen_US
dc.subjectBreast Canceren_US
dc.subjectSmall Rna Sequencingen_US
dc.titleExploring Mitomirs in Breast Cancer: an In-Vitro Study of Their Emerging Rolesen_US
dc.typeArticleen_US
dc.identifier.volume86en_US
dc.identifier.issue1en_US
dc.identifier.startpage69en_US
dc.identifier.endpage77en_US
dc.departmentPamukkale Universityen_US
dc.authoridTOKGUN, Pervin Elvan/0000-0001-9025-4140-
dc.authoridTokgun, Pervin Elvan/0000-0001-9025-4140-
dc.identifier.doi10.26650/IUITFD.1200910-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorwosidTokgun, Pervin Elvan/Aat-5377-2020-
dc.identifier.scopus2-s2.0-85149006316en_US
dc.identifier.scopus2-s2.0-85149006316-
dc.identifier.trdizinid1170301en_US
dc.identifier.wosWOS:000924056200001en_US
dc.identifier.wosWOS:001443122100004-
dc.institutionauthor…-
dc.identifier.scopusqualityQ4-
dc.description.woscitationindexEmerging Sources Citation Index-
dc.identifier.wosqualityN/A-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
crisitem.author.dept14.03. Basic Medical Sciences-
Appears in Collections:Sağlık Araştırma ve Uygulama Merkezi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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