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https://hdl.handle.net/11499/5630| Title: | The role of octreotide in the prevention of postoperative adhesion formation | Authors: | Alatas, E. | Keywords: | Adhesion formation Octreotide octreotide adhesion animal model article controlled study drug effect drug efficacy epithelization female gynecologic surgery intramuscular drug administration nonhuman peritoneum postoperative complication rat |
Abstract: | OBJECTIVE: To assess the efficacy of octreotide for reducing postoperative adhesions. STUDY DESIGN: Peritoneal defect was performed to 28 non-pregnant Wistar Albino rats. Animals were divided in to two groups randomly. Octreotide was given intramuscularly to the first group, and placebo was given to the control group. RESULTS: Incidence of postoperative adhesion formation was similar in both groups. Animals treated with octreotide had significantly reduced postoperative adhesion scores when compared with controls (p < 0.001). CONCLUSION: Treatment of peritoneal defect with octreotide resulted in significant reduction in postoperative adhesion scores. | URI: | https://hdl.handle.net/11499/5630 | ISSN: | 1016-5126 |
| Appears in Collections: | Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu |
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