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Title: | A case of SAPHO syndrome presenting with positive HLA-B27 and multiple bone involvement: Case report | Authors: | Fenkci, S. Demir, S. |
Keywords: | Acquired hyperostosis syndrome HLA-B27 antigen C reactive protein glucocorticoid HLA B27 antigen indometacin methotrexate methylprednisolone nonsteroid antiinflammatory agent salazosulfapyridine adult arthralgia article case report clinical feature computer assisted tomography drug dose reduction drug response female hand radiography human joint swelling monarthritis physical examination protein blood level psoriasis remission sacroiliitis SAPHO syndrome temporomandibular joint |
Publisher: | Turkiye Klinikleri | Abstract: | The SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) is a rare syndrome with precise bone lesions and dermatologic manifestations. We report an unusual case of SAPHO syndrome with joint involvement preceding the appearance of psoriasis by years. Another unusual feature noted in our case was the multiple involvement of bone and joints. These patients can successfully be treated with steroids and methotrexate with a long-term remission. We present our case in the light of evidence obtained by an extensive review of the literature, to support the view that SAPHO may not be rare at all, but may easily be confused with seronegative spondyloarthropathy and/or psoriatic: arthritis. Copyright © 2008 by Türkiye Klinikleri. | URI: | https://hdl.handle.net/11499/7292 | ISSN: | 1300-0292 |
Appears in Collections: | Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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