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https://hdl.handle.net/11499/8691| Title: | A child case of acute brucellosis presenting with coombs-positive autoimmune hemolytic anemia. Case report | Authors: | Akın, Mehmet Küçüktaşçı, Kazım Karaca, Abdullah Güçtürk, I. Kaya, Burçin Halis, Hülya |
Keywords: | Anemia, hemolytic, autoimmune Brucellosis Coombs' test alanine aminotransferase amoxicillin aspartate aminotransferase bilirubin complement component C3d cotrimoxazole creatinine gentamicin hemoglobin immunoglobulin G lactate dehydrogenase nitrogen prednisolone urea acute kidney failure agglutination test alanine aminotransferase blood level antibiotic therapy article aspartate aminotransferase blood level bilirubin blood level Brucella brucellosis case report child complement blood level Coombs positive hemolytic anemia corticosteroid therapy creatinine blood level differential diagnosis disease severity early diagnosis erythrocyte disorder eye jaundice female fever fluid therapy heart auscultation heart palpitation hematuria hemoglobin blood level hemoglobinuria hepatosplenomegaly human immunoglobulin blood level jaundice lactate dehydrogenase blood level lung auscultation pallor palpation preschool child reticulocyte count serology tachycardia tachypnea thrombocyte count treatment duration urea nitrogen blood level urine sediment |
Abstract: | Human brucellosis is a multisystem disease with a wide spectrum of clinical manifestations. Brucellosis can mimic several primary hematological diseases. Several non-specific hematologic abnormalities have been reported with brucellosis including anemia, leukopenia, thrombocytopenia and pancytopenia. We discussed about steroid therapy and described a child case of acute brucellosis presenting with Coombs-positive AIHA. A 3.5-year-old girl was admitted to our hospital by pallor, palpitation, fever , scleral icterus. Laboratory test showed hemoglobin 7.4 g/dL, direct Coombs IgG plus C3d test strongly positive (3+). Serology for Brucella was strongly positive (Wright agglutination reaction [1/2560], coombs agglutination reaction [1/5120]). The differential diagnosis child of Coombs-positive AIHA should include brucellosis, especially in patients living in endemic areas.Early diagnosis and treatment of disease at AIHA depentdent brucellos is important because of they could be determined to severe acute hemolysis. | URI: | https://hdl.handle.net/11499/8691 | ISSN: | 0393-3660 |
| Appears in Collections: | Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu |
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