Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/9438
Title: Novel magnesium and zinc porphyrazines containing galactose moieties: Synthesis via click reaction and characterization
Authors: Bayğu, Yasemin
Yıldız, Burak
Kabay, Nilgün
Gök, Yaşar
Keywords: Click reaction
Deprotection of ketal
Galactose
Iodination reaction
Magnesium porphyrazine
Zinc porphyrazine
Publisher: Elsevier
Abstract: In this study, galactose conjugated new magnesium and zinc porphyrazines were synthesized by the cyclotetramerization reaction of 2,3-bis[1-(2,2,7,7-tetramethyltetra-hydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5,methyl)-1H-[1,2,3]triazol-4-yl methylsulfanyl]-but 2-enedinitrile. This substituted dicyano compound was prepared via two different routes. One started from cis-1,2-dicyano-1,2-ethylenedithiolate disodium, [1-(2, 2, 7,7-tetramethyltetrahydrobis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl-methyl)-1H-[1,2,3]triazo-l-4-yl]methanol and ended in a multi-step reaction sequence via Click procedures. The other reaction was between 5-azidomethyl-2,2,7,7-tetramethyltetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran and (2Z)-2,3-bis(prop-2-yl-1-yl-thio)but-2-enedinitrile. A very soluble galactose linked magnesium porphyrazine derivative in common polar solvents and water was achieved by the deprotected isopropylidene groups in TFA and water media. It is first time, zinc porphyrazine complex has been achieved at one-step reaction by using Zn(BuO)2 as template agent. The new compounds have been characterized by a combination of elemental analysis, 1H, 13C NMR, IR, UV–vis and MS spectral data. © 2016 Elsevier B.V.
URI: https://hdl.handle.net/11499/9438
https://doi.org/10.1016/j.inoche.2016.07.001
ISSN: 1387-7003
Appears in Collections:Fen-Edebiyat Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Teknoloji Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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