Denizli Sağlık Hizmetleri Meslek Yüksekokulu Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11499/46014
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Article Noise Experiences of Patients Undergoing Total Knee Arthroplasty During the Intraoperative Process: A Mixed-Design Study(W.B. Saunders, 2026-04) H., Özsoy; H., Salık; M.H., Öztürk; Özsoy, Hatice; Salık, Hava; Öztürk, Mehmet HalilPurpose The study was conducted to determine the experiences of patients who underwent total knee arthroplasty regarding the noise they were exposed to in the operating room and recovery unit. Design The study employed a mixed-methods design. Methods The study was conducted between March and June 2024 in a public hospital located in the Mediterranean region of Turkey. The sample consisted of 20 patients who underwent total knee arthroplasty. Quantitative data were collected using the Patients’ Descriptive Characteristics Form, Surgical Fear Questionnaire, Surgical Period Data Collection Form, and Numerical Rating Scale. Qualitative data were obtained through a Semi-Structured Interview Form. The data were analyzed using MAXQDA 2022 and SPSS (24.0) software. Findings The mean age of the patients participating in the study was 66.4 ± 7.72 years and 75% were female. Preoperative anxiety was present in 70% of the patients, whereas 60% stated that they were not disturbed by intraoperative noise. The mean total score of the Surgical Fear Questionnaire was 36.15 ± 14.81, indicating a moderate level of surgical fear. Patients who were disturbed by intraoperative noise had a higher mean total score on the Surgical Fear Questionnaire. In the qualitative phase of the study, three main themes and nine codes related to these themes were identified, reflecting the patients' experiences of noise. The main themes were defined as “Sounds,” “Emotions,” and “Coping.” Conclusions This study revealed that patients with high preoperative anxiety experienced more surgical fear during surgery and were more disturbed by auditory stimuli. Motor and hammer sounds increased feelings of fear in some patients, while music was found to be disturbing and associated with headaches by some participants. Some patients were observed to turn to spiritual coping strategies to cope with these stimuli. © 2025 The American Society of PeriAnesthesia Nurses.Article Two New Mite Species of Zercon (Acari: Zerconidae) From Türkiye(Taylor & Francis Ltd, 2025-12-22) Urhan, Mehmet; Katilmis, Yusuf; Karaca, MehmetTwo new species of oligophagous mites, Zercon aysenurae sp. n. and Z. saldalacus sp. n., were described and illustrated herein. Both of them were found in Burdur province in the southwestern Turkiye. Distinctive morphological characters of the new species and their diagnostic differences from other closely related congeners were presented.https://zoobank.org/urn:lsid:zoobank.org:pub:BC3364EB-1D59-4D0F-8312-34B84B1C2944Article Exploring the Influence of Alkaline Earth Fluorides on the Structural and Spectroscopic Properties of Dy3+ Doped Oxyfluoride Borogermanate Glasses for Photonic Applications(Elsevier Ltd, 2026-04) Kocyigit-Kaplan, Deniz; Gokce, Melis; Gokce, Aytac GurhanRecent advances in photonic technologies have become integral to modern life, with applications in light emitting diodes, lasers and displays, all requiring highly efficient luminescent materials. To meet this requirement DyF<inf>3</inf> doped oxyfluoride borogermanate glasses were fabricated by the melt-quenching technique to investigate the effect of alkaline earth fluorides such as BaF<inf>2</inf>, SrF<inf>2</inf> and CaF<inf>2</inf>. The density, molar volume, refractive index, critical distance and polaron radius all follow the same increasing trend in CaF<inf>2</inf><SrF<inf>2</inf><BaF<inf>2</inf>. FT-IR analysis revealed that the CaF<inf>2</inf> doped glass network exhibits a more compact structure due to the higher concentration of [BO<inf>4</inf>] units. The ligand field around the Dy3+ ions and the ionic nature of the glass network were verified by estimating bonding parameters. The Judd-Ofelt intensity parameters indicate a stronger Dy-O covalency and lower asymmetry in the CaF<inf>2</inf> doped (BGA-Ca) sample than in the other samples. For the 4F<inf>9/2</inf>→6H<inf>13/2</inf> transition, the BGA-Ca glass exhibits the highest values of branching ratio, stimulated emission cross-section and optical gain bandwidth among all the glasses investigated. The decay time values of the 4F<inf>9/2</inf> level were found by fitting a single exponential curve. The chromaticity coordinates of oxyfluoride borogermanate glasses are centered near the white light region and the color correlated temperature and color purity values are in the neutral white light region. Among all glasses, BGA-Ca glass has the highest color purity value (42%). The results demonstrate the usability of all studied glasses in photonic applications such as laser action and white light generation. © 2025 Elsevier LtdBook Part Sexual Health in School-Age Children(Nova Science Publishers, Inc., 2025) Vural, B.K.School years mark a transition as children venture beyond their homes into the broader world. During this period, risky sexual behaviors often emerge, leading to significant health concerns. Many of these issues stem from insufficient education and unhealthy socialization surrounding sexuality, fueled by taboo perceptions and hearsay. Sexual health education aims to address young people's need for reliable information about sexuality but also focuses on taking responsibility for their sexual behavior. Parents serve as children's initial sexual educators, while teachers and school nurses, well-educated in this area, play a crucial role in schools. A comprehensive sexual health education curriculum should encompass content and skills tailored to tackle fundamental behavioral outcomes, foster healthy sexual development, ensure medical accuracy, be relevant to the child's developmental stages and cultural nuances, and promote sustainability. School nurses oversee this education, ensuring that students receive relevant reproductive and sexual health information while also identifying and addressing potential health risks. © 2025 Nova Science Publishers, Inc.Article Comprehensive Examination of Hypericum Perforatum and Hypericin: Anti-Obesity Mechanisms Uncovered by Network Pharmacology and Gene Expression Analysis(Springer, 2025-11-14) Tokgoz, Hilal Busra; Altan, FilizHypericum perforatum L. or St. John's Wort has long been utilized to treat metabolic and inflammatory conditions in traditional medical systems around the world. Although its antidepressant effects are well known, its role in obesity management remains insufficiently studied. This study aimed to investigate the anti-obesity potential of Hypericum perforatum extract and its major active constituent, hypericin. A combined in vitro and in silico experimental approach was used to explore their effects on adipogenesis, inflammation, insulin signaling and mitochondrial dysfunction. After differentiation, 3T3-L1 preadipocytes were treated with either hypericin (1-8 mu M) or Hypericum perforatum extract (25-150 mu g/mL). The MTT assay was used to measure cell survival, Oil Red O staining was used to measure lipid accumulation, RT-qPCR was used to measure the expression of 18 obesity-related targets, and ELISA was used to measure protein levels. In silico analyses included target prediction, disease relevance, protein-protein interaction networks, and hub gene identification. GO and KEGG analyses identified key biological pathways. Molecular docking, pharmacokinetics, and toxicity profiling were also performed. Hypericum perforatum extract and hypericin modulated adipogenesis, reduced lipid accumulation, and regulated genes/proteins involved in insulin sensitivity and inflammation. Docking showed strong binding of hypericin to targets such as PPAR-gamma, IRS-1, FABP4, and TNF-alpha. Bioinformatic results indicated activation of the PPAR signaling. Hypericum perforatum and hypericin exhibit multi-target anti-obesity effects via modulation of metabolic, inflammatory, and mitochondrial pathways, supporting their potential as natural therapeutic agents.Article Comparison of the Wound-Healing Potentials of Aqueous and Methanolic Extracts of Lilium Candidum (Liliaceae) Bulbs in a Mouse Model: A Histochemical Study(Pleiades Publishing Inc, 2025-11-06) Demirbas, Serife; Ili, Pinar; Mammadov, Ramazan; Dusen, Olcay; Firil, EkremLilium candidum (Liliaceae) is a bulbous plant traditionally used in folk medicine for wound treatment. In this study, aqueous and methanolic extracts of L. candidum bulbs (referred to as BEW and BEM, respectively) were prepared, and their wound-healing potentials were comparatively investigated using histochemical methods. Ointments containing 5 and 10% BEW or BEM were topically applied to excisional skin wounds in BALB/c mice once daily for 15 days. The results demonstrated that L. candidum bulb extracts exhibited wound-healing activity. The 10% BEW ointment enhanced wound contraction and basement membrane synthesis only, whereas 5 and 10% BEM ointments promoted not only wound contraction and basement membrane synthesis but also increased collagen and elastic fibre synthesis and accumulation in the dermis. These findings indicate that BEM is more effective in promoting wound-healing than BEW. This study provides scientific support for the traditional use of L. candidum in wound treatment and suggests that the methanolic extract may be preferable due to its superior healing effects.Article Citation - WoS: 1Evaluation of Hepatitis B Seroprevalence of Denizli City(Galenos Yayincilik, 2007) Asan, Ali; Sacar, Suzan; Catak, Binali; Karahasanoglu, Fatma Banu; Zencir, Mehmet; Turgut, HuseyinThe aim of this study was to determine the seroprevalence rates of hepatitis B virus in Denizli region. Between January 2007-April 2007, totally 560 person (4-80 years of age, 216 male, 344 female) were analyzed for hepatit B virus serologic parameters. We determined HBsAg, anti-HBc and anti-HBs seropositivity, 4.8%, 20% and 31.2% respectively. HBsAg positivity was found 7.4% in man and 3.2% in woman and there was a significant difference between man and woman (p= 0.02). All the children who are under ten tears old were found HBsAg negative and antiHBs positive. As a result HBsAg positivity was found compatible with national rates. There is not community based seroprevalence study in Denizli previously, so we could not compare our study and this points the importance of prevalence studies. Hepatit B virus seropositivity increases with adolescence period, this indicates that unvaccinated adolescence should be vaccinated too.Conference Object An Innovative Probiotic, LN-AGA58, Demonstrates Immunosuppressive Effects in Treating Multiple Sclerosis(Wiley, 2025) Ozen, M. B.; Bozkurt, E. B.; Ortakci, F.; Sen, A.; Acar, O. OzgunConference Object Targeting Mitochondrial Dysfunction in Obesity and Diabetes: Therapeutic Insights Into Hypericum Perforatum and Hypericin(Wiley, 2025) Bozkurt, H. B. Tokgoz; Altan, F.Book Part The Impact of Artificial Intelligence on Virtual Teams(IGI Global, 2025-07-23) A., Gündoğan; M.A., Runco; Runco, Mark A.; Gündoğan, AysunTechnology is affecting virtual teamwork. The latest advancements affecting virtual teamwork are the result of Artificial Intelligence (AI). AI has now often used in virtual teams. In light of the growing number of virtual teams in industry, it has become crucial to equip people with the requisite skills to navigate this unique working situation. In addition, universities are undergoing a process of self- orientation with a view to meeting the modern labour force. The shift from exclusively human team members to human- AI teams has produced significant changes. These changes may become more pronounced as AI progresses. This chapter reveals how AI impacts virtual teams. © 2025 Elsevier B.V., All rights reserved.